Table 2

AUC results for each of the three centres individually and for the whole dataset overall

SiteNodules (n)Cancer (%)LCP-CNN (95% CI)Brock (95% CI)Maximal axial diameter (95% CI)
Leeds43820.388.1 (84.3 to 91.5)83.4 (78.9 to 87.5)77.6 (72.5 to 82.4)
Nottingham42322.089.0 (85.3 to 92.3)87.3 (82.8 to 91.2)82.3 (77.0 to 87.4)
Oxford5369.791.9 (88.5 to 94.9)91.3 (87.3 to 94.6)91.0 (86.8 to 94.4)
All139716.889.6 (87.6 to 91.5)*86.8 (84.3 to 89.1)*83.1 (80.3 to 85.8)
  • ‘Diameter’ simply means stratifying the nodules according to the maximal diameter on an axial slice and using that to create a receiver operating curve.

  • *P=0.0044 for LCP-CNN versus Brock.

  • AUC, area under the curve; LCP-CNN, lung cancer prediction convolutional neural network.