Cross-validated ORs (95% CIs) for culture-confirmed TB for the baseline model with clinical predictors, CXR and TST and the expanded model with binary T-SPOT.TB results (n=491)
| Predictor | Baseline model without T-SPOT.TB | Expanded model with T-SPOT.TB (binary) |
|---|---|---|
| Night sweats | 1.42 (0.72 to 2.80) | 1.32 (0.66 to 2.69) |
| Malaise | 1.82 (0.94 to 3.53) | 2.08 (1.03 to 4.18) |
| Fever >2 weeks | 1.90 (0.83 to 4.35) | 1.86 (0.78 to 4.48) |
| Cough >2 weeks | 1.52 (0.73 to 3.16) | 1.42 (0.67 to 3.03) |
| History of TB contact | 0.84 (0.43 to 1.65) | 0.61 (0.29 to 1.25) |
| HIV positive | 0.43 (0.14 to 1.34) | 0.64 (0.19 to 2.14) |
| CXR consistent with TB | 5.53 (2.03 to 15.03) | 4.62 (1.65 to 12.94) |
| TST positive | 19.30 (7.32 to 50.91) | 7.54 (2.56 to 22.20) |
| T-SPOT.TB | – | 5.93 (2.39 to 14.73) |
CXR, chest radiography; TB, tuberculosis; TST, tuberculin skin test.