Predictive potential of severity rules for admission to the ICU (for definition of rules see text)
| Sensitivity | Specificity | PPV | NPV | Overall accuracy | |
|---|---|---|---|---|---|
| Data are presented as number (%) with 95% confidence intervals (CI). | |||||
| PPV = positive predicted value; NPV = negative predicted value. | |||||
| Modified ATS rule | 80/116 (69%) | 568/580 (98%) | 80/92 (87%) | 568/604 (94%) | 648/696 (93%) |
| (59.7 to 77.2) | (96.4 to 98.9) | (78.3 to 93.1) | (91.8 to 95.8) | (91.0 to 94.9) | |
| Original derivation cohort3 | 47/60 (78%) | 268/284 (94%) | 47/63 (75%) | 268/281 (95%) | 315/344 (92%) |
| (65.8 to 87.9) | (91.0 to 69.7) | (62.1 to 84.7) | (92.2 to 97.5) | (88.1 to 94.3) | |
| Alternative ATS rule | 99/114 (87%) | 476/578 (82%) | 99/201 (49%) | 476/491 (97%) | 575/692 (83%) |
| (79.2 to 92.5) | (79.0 to 85.4) | (42.1 to 56.4) | (95.0 to 98.3) | (80.1 to 85.8) | |
| BTS I | 37/108 (34%) | 488/549 (89%) | 37/98 (38%) | 488/559 (87%) | 525/657 (80%) |
| (25.4 to 44.0) | (86.0 to 91.4) | (28.2 to 48.1) | (84.3 to 89.9) | (76.6 to 82.9) | |
| BTS II | 51/115 (44%) | 496/578 (86%) | 51/133 (38%) | 496/560 (89%) | 547/693 (79%) |
| (5.1 to 53.9) | (82.7 to 88.6) | (30.1 to 47.2) | (85.6 to 91.1) | (75.7 to 81.9) | |
| Modified BTS rule | 47/98 (48%) | 409/494 (83%) | 47/132 (36%) | 409/460 (89%) | 456/592 (77%) |
| (37.8 to 58.3) | (79.2 to 86.0) | (27.5 to 44.4) | (85.7 to 91.6) | (73.4 to 80.4) | |
| Sepsis | 100/113 (89%) | 134/570 (24%) | 100/536 (19%) | 134/147 (91%) | 234/683 (34%) |
| (81.1 to 93.7) | (20.1 to 27.2) | (15.5 to 22.2) | (85.4 to 95.2) | (30.7 to 38.0) | |
| Severe sepsis | 80/107 (75%) | 344/464 (74%) | 80/200 (40%) | 344/371 (93%) | 424/571 (74%) |
| (65.4 to 82.7) | (69.9 to 78.1) | (33.2 to 47.1) | (89.6 to 95.1) | (70.5 to 77.8) | |
| Septic shock | 56/116 (48%) | 580/580 (100%) | 56/56 (100%) | 580/640 (91%) | 636/696 (91%) |
| (38.9 to 57.7) | (99.4 to 100) | (93.6 to 100) | (88.1 to 92.8) | (89.0 to 93.4) | |