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  • Topographic heterogeneity of lung microbiota in end-stage idiopathic pulmonary fibrosis: the Microbiome in Lung Explants-2 (MiLEs-2) study

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Interstitial lung disease
Original research
Topographic heterogeneity of lung microbiota in end-stage idiopathic pulmonary fibrosis: the Microbiome in Lung Explants-2 (MiLEs-2) study

Authors

  • Eleanor Valenzi Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Haopu Yang Center for Medicine and the Microbiome, University of Pittsburgh, Pittsburgh, Pennsylvania, USA Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA School of Medicine, Tsinghua University, Beijing, China PubMed articlesGoogle scholar articles
  • John C Sembrat Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Libing Yang Center for Medicine and the Microbiome, University of Pittsburgh, Pittsburgh, Pennsylvania, USA School of Medicine, Tsinghua University, Beijing, China PubMed articlesGoogle scholar articles
  • Spencer Winters Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA Bronson Adult Critical Care, Kalamazoo, Michigan, USA PubMed articlesGoogle scholar articles
  • Rachel Nettles Center for Medicine and the Microbiome, University of Pittsburgh, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Daniel J Kass Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Shulin Qin Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA Center for Medicine and the Microbiome, University of Pittsburgh, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Xiaohong Wang Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA Center for Medicine and the Microbiome, University of Pittsburgh, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Michael M Myerburg Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Barbara Methé Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA Center for Medicine and the Microbiome, University of Pittsburgh, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Adam Fitch Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA Center for Medicine and the Microbiome, University of Pittsburgh, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Jonathan K Alder Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Panayiotis V Benos Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Bryan J McVerry Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA Center for Medicine and the Microbiome, University of Pittsburgh, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Mauricio Rojas Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Alison Morris Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA Center for Medicine and the Microbiome, University of Pittsburgh, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Georgios D Kitsios Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA Center for Medicine and the Microbiome, University of Pittsburgh, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Georgios D Kitsios, Pulmonary Allergy and Critical Care Medicine, University of Pittsburgh Medical Center Health System, Pittsburgh, PA 15260, USA; kitsiosg{at}upmc.edu
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Citation

Valenzi E, Yang H, Sembrat JC, et al
Topographic heterogeneity of lung microbiota in end-stage idiopathic pulmonary fibrosis: the Microbiome in Lung Explants-2 (MiLEs-2) study
Thorax 2021;76:239-247.

Publication history

  • Received March 5, 2020
  • Revised September 18, 2020
  • Accepted September 25, 2020
  • First published December 2, 2020.
Online issue publication 
February 16, 2021

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© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.