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Thillai and colleagues1 describe a method of image analysis, functional respiratory imaging (FRI), which creates a three-dimensional reconstruction of both airways and the pulmonary vasculature from CT-scan images, in 10 patients with severe COVID-19 infection. They computed the distribution of pulmonary blood flow according cross-sectional vessel area size and compared the data to age, gender, height and premorbidity matched acute respiratory distress syndrome (ARDS) patients (n=7) and retrospective data from healthy volunteers (n=107).
Their post processing imaging results were interesting as they find that in patients with COVID-19, the blood flow was diminished in the peripheral small calibre vessels and conversely increased in the more centrally located arteries in comparison to both the ARDS and the healthy control group, without differences in right …
Footnotes
Contributors LJM and JvE designed and wrote the manuscript.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent for publication Not required.
Provenance and peer review Commissioned; externally peer reviewed.