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Choosing the surgical mortality threshold for high risk patients with stage Ia non-small cell lung cancer: insights from decision analysis
  1. J Dowie,
  2. M Wildman
  1. Public Health and Policy Department, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
  1. Correspondence to:
    Professor J Dowie, Public Health and Policy Department, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK;
    jack.dowie{at}lshtm.ac.uk

Abstract

The recent British Thoracic Society guidelines recommend that surgical mortality should not be greater than 8% for pneumonectomy and 4% for lobectomy. These cut offs are advanced as guidelines to inform decision making as to whether or not patients with operable lung cancer should be offered surgery. They have been developed from a notion of what acceptable surgical mortality should be. The planning of care for patients with lung cancer involves making choices between different treatments with different outcomes. While it is accepted that the probability of these outcomes is likely to differ among patients, individual patient preferences for them are also likely to vary. Fixed cut offs for surgical mortality mean ignoring this variation. Decision analysis can be used to assist in the complex task of integrating clinical characteristics and varying patient preferences. By considering high risk patients with potentially curable stage Ia non-small cell lung cancer, it is shown that decision analysis has the potential to illuminate decision making and guideline development within the field of cancer care.

  • decision analysis
  • lung cancer

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Footnotes

  • Conflicts of interest: None.

  • The decision tree produced using the specialist decision analytic software DATA 3.5 by TreeAge will be automatically sent on receipt of an email message to jack.dowie{at}lshtm.ac.uk with the subject SEND THORAX. A demonstration version of DATA 3.5 may be downloaded from the TreeAge website at http://www.treeage.com. The additional tree mentioned in the discussion will also be sent. This will allow readers to input their own centre specific data (e.g. patient utilities or radiotherapy survival data) and test for surgical cut off.