Fibrosis stage comparison with histological/radiological parameters
| Variable | N | Stage 1 | Stage 2 | Stage 3 | Stage 4 | P value |
| Pericellular elastic fibres | 40 | 0.423 | ||||
| Absent | 1 | 0 | 1 | 0 | ||
| Stage 1 | 6 | 10 | 12 | 1 | ||
| Stage 2 | 0 | 4 | 4 | 1 | ||
| CPA* | 40 | |||||
| Parenchyma | 4.18 (2.82) | 4.71 (3.32) | 3.28 (7.15) | 9.32 | 0.321 | |
| Combined | 8.22 (4.25) | 8.34 (4.72) | 12.38 (8.49) | 29.34 | 0.0162 | |
| CD3-positive cells density* | 28 | |||||
| Parenchyma | 145.81 (79.07) | 206.03 (147.64) | 276.65 (349.67) | – | 0.197 | |
| Portal/stromal | 295.90 (302.67) | 393.90 (539.06) | 743.00 (1198.02) | – | 0.115 | |
| Combined | 144.99 (87.42) | 208.40 (130.14) | 304.50 (511.36) | – | 0.125 | |
| EPA* | 40 | 0.12 (0.23) | 0.46 (1.35) | 1.69 (3.72) | 4.96 | 0.0123 |
| CD34 | 28 | 0.0377 | ||||
| Not increased | 0 | 0 | 0 | 0 | ||
| Marginal | 1 | 0 | 1 | 0 | ||
| Focal | 4 | 3 | 3 | 0 | ||
| Diffuse incomplete | 0 | 6 | 9 | 0 | ||
| Diffuse complete | 0 | 1 | 0 | 0 |
*Reported as median and IQR (in brackets), when possible.
CPA, collagen proportionate area; EPA, elastin proportionate area; NRH-LC-A, nodular regenerative hyperplasia-like changes absent; NRH-LC-P, NRH-LC-present.