HomeCurrent Issue
Current Issue
January 2025 - Volume 4 - 1
Editorial
24 March 2025•
Does radiation-induced lymphocytopenia matter? Developing a radiotherapy dosimetric strategy for immune preservation and improved survivalMohammed Abdul-Latif, John Conibear, Niluja Thiruthaneeswaran, Yat Man Tsang
21 March 2025•
Understandable, individualised information about risk is essential to help patients make fully informed decisions about breast cancer treatmentShelley Potter
7 March 2025•
Surveillance imaging: minimal evidence and forgotten harmsHaydee Verduzco-Aguirre, Christopher M Booth, Brooke E Wilson
6 March 2025•
Re-evaluating testosterone therapy: new insights for men with familial prostate cancer riskOmer Onur Cakir, Fabio Castiglione
6 March 2025•
Checkpoint inhibitor therapy in immunosuppressed patients with Merkel cell carcinoma: not all immunosuppression is created equalAndrew S Brohl
18 February 2025•
Predicting short-term risk of colorectal cancer using primary care records, genetics and lifestyle factorsChristiana Kartsonaki
29 January 2025•
Patina of precision: risk models for lung cancer screening eligibilityPeter B Bach, Benjamin L Mazer
24 February 2025•
Evaluating the genetic landscape of prostate cancer: new insights from BRCA1/2, ATM and CDK12 mutationsFumihiko Urabe, Kosuke Takemura
Original research
5 April 2025•
Supercharged NK cells, unlike primary activated NK cells, effectively target ovarian cancer cells irrespective of MHC-class I expressionSara Huerta-Yepez, Po-Chun Chen, Kawaljit Kaur, Yash Jain, Tanya Singh, Favour Esedebe, Yi Jou Liao, Gabriella DiBernardo, Neda A Moatamed, Ao Mei, Subramaniam Malarkannan, Thomas G Graeber, Sanaz Memarzadeh, Anahid Jewett
1 April 2025•
Geographic, socioeconomic and demographic inequalities in the incidence of metastatic prostate cancer at time of diagnosis in England: a population-based evaluationJoanna Dodkins, Adrian Cook, Emily Mayne, Marina Parry, Julie Nossiter, Heather Payne, Thomas E Cowling, Alison Tree, Ajay Aggarwal, Noel Clarke, Jan van der Meulen
1 April 2025•
Mental healthcare utilisation among individuals with colorectal cancer: population-based cohort studiesVicki Cheng, Eric C Sayre, Vienna Cheng, Jonathan M Loree, Sharlene Gill, Rachel A Murphy, Alyssa Howren, Mary A De Vera
21 March 2025•
Improving patient understanding of GEP test results (IMPARTER4): an RCTLesley Fallowfield, Ivonne Solis-Trapala, Rachel Starkings, Lucy Matthews, Shirley May, Valerie Jenkins
16 March 2025•
TERT promoter mutations or protein overexpression define an aggressive subset with favourable immunotherapeutic response in advanced urothelial carcinomaKaifeng Jin, Jingtong Xu, Lingkai Zhang, Zhaopei Liu, Xiaohe Su, Ziyue Xu, Yawei Ding, Hailong Liu, Yuan Chang, Le Xu, Zewei Wang, Yu Zhu, Jiejie Xu
7 March 2025•
A systematic review comparing surveillance recommendations for the detection of recurrence following surgery across 16 common cancer typesHannah Harrison, Bhumi K Shah, Faris Khan, Carley Batley, Chiara Re, Sabrina H Rossi, Georgia Stimpson, Eamonn Gilmore, Eleanor White, Sofia Kler-Sangha, Aufia Espressivo, Z Sienna Pan, Tanzil Rujeedawa, Benjamin W Lamb, Laura Succony, Shi Lam, Bincy M Zacharia, Rebecca Lucey, Alexander J P Fulton, Dimana Kaludova, Anita Balakrishnan, Juliet A Usher-Smith, Grant D Stewart
6 March 2025•
Incidence of prostate cancer in men with testosterone deficiency and a family history of prostate cancer receiving testosterone therapy: a comparative studyEdoardo Pozzi, Corey A Able, Taylor Kohn, Bruce R Kava, Francesco Montorsi, Andrea Salonia
6 March 2025•
Impact of resection margin width on local recurrence following breast-conserving surgery and whole breast radiotherapy for pure ductal carcinoma in situ: a systematic review and meta-analysisAhmed Ezzat, Dhurka Shanthakumar, Naomi Laskar, Ramsey I Cutress, Dimitri Hadjiminas, Michael Boland, Meera Joshi, Ronak Patel, Yasmin Grant, Ravi Naik, Nur Amalina Che Bakri, Saur Hajev, Hussein Elghazaly, Josephine Holt, Alfie Roddan, Susan Cleator, Ara Darzi, Hutan Ashrafian, Daniel R Leff
6 March 2025•
Immunotherapy response in immunosuppressed patients with Merkel cell carcinoma: analysis of 183 patientsEmily Gong, Lauren Zawacki, Xinyi Fan, Daniel S Hippe, Ankita A Menon, Allison J Remington, Kristina Lachance, Tomoko Akaike, Lisa Tachiki, Song Y Park, Paul Nghiem
3 March 2025•
Associations of DNA methylation in breast tumour subtypes with parity and breastfeeding in a cohort of 1459 Black women: implications for public healthChristine B Ambrosone, Song Yao, Mark D Long, Chunyu Liu, Jianhong Chen, Warren Davis, Gary Zirpoli, Rochelle Payne-Ondracek, Thaer Khoury, Zhihong Gong, Qiang Hu, Sirinapa Szewczyk, Angela R Omilian, Elisa V Bandera, Song Liu, Lawrence Kushi, Michael J Higgins, Julie R Palmer
25 February 2025•
Long-term outcomes of bilateral salpingo-oophorectomy in women with personal history of breast cancerHend Hassan, Tameera Rahman, Andrew Bacon, Craig Knott, Isaac Allen, Catherine Huntley, Lucy Loong, Yvonne Walburga, Eva Morris, Steven Hardy, Bethany Torr, Diana M Eccles, Clare Turnbull, Marc Tischkowitz, Paul Pharoah, Antonis C Antoniou
25 February 2025•
Whole-body integral dose and post-radiotherapy lymphocytopaenia in solid tumoursNuradh Joseph, Lanka Alagiyawanna, Thilina Ruwanpura, Sanjeeva Gunasekera, Lakitha Ruvinda, Sampath Madushan, Ananya Choudhury
18 February 2025•
Genetics, primary care records and lifestyle factors for short-term dynamic risk prediction of colorectal cancer: prospective study of asymptomatic and symptomatic UK Biobank participantsSamantha Ip, Hannah Harrison, Juliet A Usher-Smith, Matthew E Barclay, Jonathan Tyrer, Joe Dennis, Xin Yang, Michael Lush, Cristina Renzi, Nora Pashayan, Spiros Denaxas, Georgios Lyratzopoulos, Antonis C Antoniou, Angela M Wood
24 February 2025•
UK-based clinical testing programme for somatic and germline BRCA1/2, ATM and CDK12 mutations in prostate cancer: first resultsD Gareth Evans, George Burghel, Helene Schlecht, Ashwin Sachdeva, Andrew Hudson, Omi Parikh, Fiona Lalloo, Robert Bristow, Emma R Woodward
16 January 2025•
Molecular and immune landscape of tumours in geriatric patients with non-small cell lung cancer, melanoma and renal cell carcinomaKhalil Choucair, Andrew Elliott, Matthew James Oberley, Phillip Walker, April K Salama, Azhar Saeed, Hirva Mamdani, Dipesh Uprety, Wafik S El-Deiry, Himisha Beltran, Stephen V Liu, Chul Kim, Abdul Rafeh Naqash, Emil Lou, Lujia Chen, Anwaar Saeed
Review
25 March 2025•
Air pollution and its impact on cancer incidence, cancer care and cancer outcomesRoselle De Guzman, Joan Schiller
9 January 2025•
Thirty years from FDA approval of pegylated liposomal doxorubicin (Doxil/Caelyx): an updated analysis and future perspectiveAlberto A Gabizon, Shira Gabizon-Peretz, Shadan Modaresahmadi, Ninh M La-Beck
7 January 2025•
Advancing cancer care through digital access in the USA: a state-of-the-art review of patient portals in oncologyUday Suresh, Jessica Ancker, Liz Salmi, Lisa Diamond, Trent Rosenbloom, Bryan Steitz