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Neurological rarities
Cyclosporine-induced erythromelalgia
  1. Francisco Caiza-Zambrano1,
  2. Julio Galarza1,
  3. Mauricio Benetti1,
  4. Fabio Gonzalez1,
  5. Paula Landriscina2,
  6. Ricardo Reisin1,
  7. Luciana León-Cejas1
  1. 1 Department of Neurology, Hospital Británico de Buenos Aires, Buenos Aires, Argentina
  2. 2 Department of Neurology, Hospital General de Agudos Dr Cosme Argerich, Buenos Aires, Argentina
  1. Correspondence to Dr Francisco Caiza-Zambrano, Department of Neurology, Hospital Británico de Buenos Aires, Buenos Aires, Argentina; pancho_jcz{at}hotmail.com

Abstract

Erythromelalgia is a rare syndrome characterised by recurrent erythema, heat and burning pain in the extremities. There are two types: primary (genetic) and secondary (toxic, drug-related or associated with other diseases). We report a 42-year-old woman who developed erythromelalgia after taking cyclosporine for myasthenia gravis. Although exact mechanism for this rare adverse effect is unclear, it is reversible, and so clinicians should be aware of the association . Additional use of corticosteroids could aggravate cyclosporine’s toxic effects.

  • NEUROMUSCULAR
  • NEUROPATHY
  • MYASTHENIA

Data availability statement

All data relevant to the study are included in the article or uploaded as supplementary information.

https://doi.org/10.1136/pn-2023-003770

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    Data availability statement

    All data relevant to the study are included in the article or uploaded as supplementary information.

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    Footnotes

    • Twitter @panchoCZ

    • Contributors All authors provided intellectual contribution to this article.

    • Funding This work is not financially supported by any project or organisations.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned. Externally peer reviewed by Mabs Chowdhury, Cardiff, UK, and David Bennett, Oxford, UK.