Study schedule
| Preoperatory medical examination (T0) | Surgical procedure | 24 hours post-op (T1) | 1-month follow-up (T2) | 3-month follow-up (T3) | 6-month follow-up (T4) | 12-month follow-up (T5) | |
| Inclusion/exclusion criteria evaluation | X | X | |||||
| Informed consent signing | X | ||||||
| Demographic data | X | ||||||
| Medical history | X | ||||||
| Randomisation | X | ||||||
| WOMAC | X | X | X | X | X | ||
| IKDC subjective | X | X | X | X | X | ||
| IKDC objective | X | X | X | X | X | ||
| KOOS | X | X | X | X | X | ||
| EQ-VAS | X | X | X | X | X | ||
| Tegner | X | X | X | X | X | ||
| Patient expectation on the treatment | X | ||||||
| Patient judgement on the treatment | X | X | |||||
| Adverse events reporting | X | X | X | X | X | X | |
| Medication tracking sheet | X | X | X | X | |||
| Biomechanical analysis | X | X | |||||
| Radiography and KL evaluation | X | X | X | X | |||
| 3T MR and WORMS | X | X | |||||
| Serum/plasma and urine collection | X | X | X | X | X | X | |
| Synovial membrane and SF collection | X |
EQ-VAS, EuroQol-Visual Analogue Scale; IKDC, International Knee Documentation Committee; KL, Kellgren-Lawrence; KOOS, Knee Injury and Osteoarthritis Outcome Score; MR, magnetic resonance; SF, synovial fluid; T, Tesla; WOMAC, Western Ontario and McMaster Universities Arthritis Index; WORMS, Whole-Organ MRI Score.