Framing of this systematic review with key items identified by the CHARMS checklist
Items | Comments |
1. Prognostic versus diagnostic prediction model | Prognostic prediction model (aimed to predict future survival outcomes of TE-PLHIV) |
2. Intended scope of the review | Prognostic prediction models to inform clinicians’ therapeutic decision-making regarding the management of HIV/AIDS |
3. Type of prediction modelling studies | All study types including prognostic prediction modelling studies with or without external validation and external model validation studies with or without model updating |
T4. arget population to whom the prediction model applies | TE-PLHIV according to each included study |
5. Outcome to be predicted | Survival after ART initiation, including all-cause mortality and/or HIV-related mortality |
6. Time span of prediction | Survival outcomes occurring at any time point after ART initiation |
7. Intended moment of using the model | At any time point after ART initiation |
ART, antiretroviral therapy; CHARMS, CHecklist for critical Appraisal and data extraction for systematic Reviews of prediction Modelling Studies; TE-PLHIV, treatment experienced people living with HIV/AIDS.