MIC values of knee osteoarthritis outcome tools derived using the anchor method
| Outcome tools | Score | Median | Minimum | Maximum | No of estimates | Study |
| ICOAP-pain | 100=worst | 18.5 | 1 | Singh, 201441 | ||
| ICOAP-constant pain | 100=worst | 18.7 | 1 | Singh, 201441 | ||
| ICOAP-intermittent pain | 100=worst | 18.4 | 1 | Singh, 201441 | ||
| KOOS-pain | 100=best | 12.4 | 4.3 | 20.1 | 4 | Mills, 201615 |
| KOOS-activities of daily living | 100=best | 8.4 | 8.2 | 8.7 | 2 | Mills, 201615 |
| KOOS-quality of life | 100=best | 9.8 | 8.0 | 11.6 | 2 | Mills, 2016; Singh, 201415 41 |
| KOOS-PS | 100=worst | 2.2 | 1 | Singh, 201441 | ||
| Pain on NRS at rest | 100=worst | 10.0 | 10 | 10 | 2 | Perrot, 201343 |
| Pain on VAS on movement | 100=worst | 19.9 mm | 1 | Tubach, 200514 | ||
| Patient-reported functional disability on an NRS | 100=worst | 27.6 | 27.2 | 27.9 | 2 | Ornetti, 201140 |
| Patient’s global assessment of disease activity on VAS | 100=worst | 18.3 mm | 1 | Tubach, 200514 | ||
| Physician-reported functional disability on an NRS | 100=worst | 25.3 | 25 | 25.5 | 2 | Ornetti, 201140 |
| WOMAC-function | 100=worst | 17.0 | 9.1 | 17.1 | 3 | Tubach, 2005; Ornetti, 201114 40 |
| Estimates based on low-quality studies | ||||||
| ICOAP-pain | 100=worst | 13.4 | 1 | Harris, 201335 | ||
| KOOS-PS | 100=worst | 12.0 | 1 | Harris, 201335 | ||
| OKS-pain | 100=best | 17.3 | 1 | Harris, 201335 | ||
| OKS-function | 100=best | 10.6 | 1 | Harris, 201335 | ||
| OKS-summary | 100=best | 7.1 | 1 | Harris, 201335 | ||
All the scores are from 0 to 100.
The median estimates are shaded in blue.
Estimates based on low-quality studies are shaded in grey.
.ICOAP, Intermittent and Constant Osteoarthritis Pain; KOOS, Knee injury and Osteoarthritis Outcome Score; KOOS-PS, Knee injury and Osteoarthritis Outcome Score Physical Function Short form; MIC, minimal important change; NRS, Numeric Rating Scale; OKS, Oxford Knee Score; VAS, Visual Analogue Scale; WOMAC, Western Ontario and McMaster Universities Arthritis Index.