Table 1

Samples analysed during the study

Screening
S-FSH	P-ASAT	P-Sodium
S-LH	P-Calcium
S-SHBG	fP-Glucose	Full blood cell count
S-Testosterone	P-GT	B-HbA1c
S-TSH	P-HDL Cholesterol
S-T4	P-Potassium	U-screening for substance abuse*
P-Albumin	P-Cholesterol	U-Pregnancy test†
P-ALAT	P-Creatinine
P-ALP	fP-LDL Cholesterol	Research samples‡
At 4 weeks
P-ALAT	P-GT	Full blood cell count
P-ALP	P-Potassium
P-ASAT	P-Creatinine	U-Pregnancy test†
P-Glucose	P-Sodium
At 8 weeks
P-ALAT	P-Creatinine	U-Pregnancy test†
P-ALP	P-Sodium	P-Fluoxetine or U-Naltrexone§
P-ASAT	Full blood cell count
P-GT	B-HbA1c	Research samples‡
P-Potassium

*Amphetamine, benzodiazepines, buprenorphine, cannabis, cocaine, fentanyl, methadone, oxycodone, tramadol and other opioids.
†Assigned female at birth only.
‡ E.g. DNA extraction for genome-wide methylation analysis (EPIC) and second-generation DNA sequencing, oxytocin pretreatment and post-treatment.
§Depending on randomisation.