Mean baseline adjusted differences in primary and secondary outcome measures between treatment groups (metformin and sitagliptin combined compared with no medication)
| Unadjusted | Adjusted | |
| Baseline adjusted differences in 2 hour post-load glucose in mmol/L (95% CI) | −0.06 (−0.56 to 0.44) | −0.04 (−0.53 to 0.45) |
| Baseline adjusted differences in fasting glucose levels in mmol/L (95% CI) | −0.22 (−0.37 to −0.06) | −0.21 (−0.36 to −0.06) |
| Baseline adjusted differences in HbA1c levels in mmol/mol (95% CI) | −1.14 (−1.8 to -0.47) | −1.16 (−1.84 to −0.49) |
| Baseline adjusted differences in LDL levels in mmol/L (95% CI) | −0.12 (−0.28 to 0.04) | −0.11 (−0.27 to 0.06) |
| Baseline adjusted differences in BMI in kg/m2 (95% CI) | 0.1 (−0.37 to 0.57) | 0.06 (−0.41 to 0.52) |
| Baseline adjusted differences in systolic blood pressure levels in mm Hg (95% CI) | −2.91 (−7.59 to 1.77) | −2.46 (−6.98 to 2.06) |
| Baseline adjusted differences in diastolic blood pressure levels in mm Hg (95% CI) | −1.8 (−5.08 to 1.47) | −1.57 (−4.91 to 1.78) |
Adjusted for age, sex, time to treatment, BMI and baseline glucose levels.
BMI, body mass index; HbA1c, glycosylated haemoglobin 1 c; LDL, low-density lipoprotein.