Percentage of patients with normalised 2-hour postload glucose, fasting glucose and HbA1c levels after 6 months compared with baseline
| Control (n=53) | Metformin (n=26) | Sitagliptin (n=22) | P value | Adjusted OR (95% CI) | |
| Normalised 2 hours postload glucose (<7.8 mmol/L) at 6 months, n (%) | 17 (39) | 7 (33) | 7 (41) | 0.872 | 1.07 (0.59 to 1.95) |
| Normalised fasting glucose (<5.6 mmol/L) at 6 months, n (%) | 22 (48) | 16 (70) | 16 (89) | <0.007 | 3.01 (1.49 to 6.11) |
| Difference in patients with normalised fasting glucose at 6 months compared with baseline, (%) | −5 | 16 | 34 | ||
| Normalised HbA1c (<39 mmol/mol), n (%) | 21 (47) | 11 (55) | 11 (65) | 0.432 | 1.83 (0.8 to 4.16) |
| Difference in patients with normalised HbA1c at 6 months compared with baseline, (%) | −13 | 7 | 10 |
Adjusted for age, sex, time to treatment, BMI and baseline glucose levels.
BMI, body mass index; HbA1c, glycosylated haemoglobin 1 c.