Table 3

Prognostic factors for men with localised disease associated with outcomes

n=10 901			Prostate cancer mortality			All-cause mortality			Systemic therapy
Factor	Mean (SD)	Missing (n (%))	HR per SD**	95% CI	P	HR per SD**	95% CI	P	HR per SD**	95% CI	P
Age	74.39 (9.03)	0	1.70	1.40 to 2.06	<0.01	1.92	1.74 to 2.12	<0.01	1	0.95 to 1.06	0.98
BMI	27.43 (4.48)	394 (3.61%)	1.05	0.90 to 1.08	0.52	0.97	0.90 to 1.05	0.51	1.04	0.99 to 1.09	0.10
Triglycerides	1.45 (0.80)	3856 (35.37%)	0.83	0.64 to 1.08	0.16	1.00†	0.90 to 1.13	0.93	1.03	0.97 to 1.09	0.37
HDL cholesterol	1.35 (0.43)	3954 (36.27%)	1.05	0.89 to 1.23	0.56	1.01†	0.91 to 1.12	0.86	1.01	0.95 to 1.07	0.75
LDL cholesterol	2.95 (0.99)	4698 (43.10%)	0.86	0.69 to 1.07	0.18	0.92†	0.82 to 1.02	0.12	0.99	0.94 to 1.05	0.86
Hb	144.28 (14.35)	2696 (24.73%)	0.72	0.59 to 0.88	<0.01	0.74	0.67 to 0.82	<0.01	0.92	0.86 to 0.98	0.01
Albumin	41.83 (3.94)	2954 (27.10%)	0.81	0.67 to 0.97	0.02	0.83	0.76 to 0.91	<0.01	0.94	0.89 to 0.99	0.04
Random glucose	5.70 (2.11)	4525 (41.51%)	1.27	1.06 to 1.54	0.01	1.12	0.99 to 1.25	0.06	1.02†	0.95 to 1.09	0.66

	Median (IQR)	Missing (n (%))
PSA	8.4 (5.55, 14.60)	2352 (21.58%)	1.71	1.32 to 2.23	<0.01	1.46	1.19 to 1.78	<0.01	1.34	1.06 to 1.68	0.01
CRP	3.9 (2, 8)	8061 (73.95%)	1.35†	1.02 to 1.77	0.03	1.23†	1.05 to 1.45	0.01	1.07	0.95 to 1.20	0.24
Ferritin	108.6 (47, 196)	9495 (87.10%)	2.03	1.21 to 3.39	<0.01	0.98†	0.60 to 1.59	0.93	1.05	0.85 to 1.31	0.64

*Adjusted for age, PSA, Gleason score, TNM stage.
†Proportional Hazards assumption test not met.
BMI, body mass index; CRP, C reactive protein; Hb, haemoglobin; HbA1c, haemoglobin A1c; HDL, high density lipoprotein; LDL, low density lipoprotein; PSA, prostate specific antigen; TNM, tumour–node–metastases.