Baseline characteristics of patients with bronchial thermoplasty (BT) in UK Severe Asthma Registry (UKSAR) compared with clinical trials
| UKSAR | AIR2 trial | AIR trial | RISA trial | |
| Mean age at BT1 (years) | 43.7±12.2 (n=125) Range 21–74 | 40.7±11.9 (*BT, n=190) 40.6±11.9 (†C, n=98) | 39.4±11.2 (BT, n=55) 41.7±11.4 (C, n=54) | 39.1±13.0 (BT, n=15) 42.1±12.6 (C, n=17) |
| % female | 70 (n=126) | 57 (BT), 61 (C) | 56 (BT), 57 (C) | 60 (BT), 41(C) |
| Pre-bronch FEV1
(% predicted) | 71.0±21.8 (n=118) Range: 18–109 | 77.8±15.7 (BT) 79.7±15.1 (C) | 72.7±10.4 (BT) 76.1±9.3 (C) | 62.9±12.2 (BT) 66.4±17.8 (C) |
| AQLQ score‡ | 3.66±1.35 (n=81) Range 1.0–6.81 | 4.30±1.17 (BT) 4.32±1.21 (C) | 5.6±1.1 (BT) 5.7±0.9 (C) | 3.96±1.34 (BT) 4.72±1.06 (C) |
*BT, subjects receiving BT treatment.
†C, control subjects.
‡A higher AQLQ score represents better quality of life.
AQLQ, Asthma Quality of Life Questionnaire; FEV1, forced expiratory volume in 1 s.