Prevalence of physical health conditions for adults with and without Down syndrome across all ICD-10 chapters
| Physical health condition | Whole cohort (n=1023) n | Whole cohort % | Down syndrome (n=186) (n (%)) | Without down syndrome (n=837) (n (%)) | |
| 1 | Visual impairment | 481 | 47 | 90 (48.4) | 391 (46.7) |
| 2 | Obesity | 415 | 40.6 | 105 (56.5) | 310 (37) |
| 3 | Epilepsy | 349 | 34.1 | 24 (13) | 325 (38.8) |
| 4 | Constipation | 346 | 33.8 | 45 (24.1) | 301 (36) |
| 5 | Ataxic/gait disorders | 306 | 29.9 | 30 (16.1) | 276 (33) |
| 6 | Hearing impairment | 276 | 26.9 | 73 (39.2) | 203 (24.2) |
| 7 | Nail disorder (eg, ingrowing nail) | 238 | 23.3 | 50 (26.9) | 188 (22.5) |
| 8 | Epidermal thickening/xerosis | 217 | 21.2 | 69 (37.1) | 148 (17.7) |
| 9 | Cerebral palsy and other paralytic syndromes | 191 | 18.7 | 8 (4.3) | 183 (21.9) |
| 10 | Osteoporosis | 189 | 18.5 | 11 (5.9) | 178 (21.3) |
| 11 | Fungal infection | 167 | 16.3 | 42 (22.5) | 125 (14.9) |
| 12 | Hypertension | 158 | 15.4 | 8 (4.3) | 150 (17.9) |
| 13 | Bone deformity | 155 | 15.1 | 27 (14.5) | 128 (15.3) |
| 14 | Musculoskeletal pain/dorsalgia | 152 | 14.9 | 32 (17.2) | 120 (14.3) |
| 15 | Eczema/dermatitis | 149 | 14.6 | 38 (20.4) | 111 (13.3) |
| 16 | Gastro-oesophageal reflux disorder | 148 | 14.5 | 26 (14) | 122 (14.6) |
| 17 | Dysphagia | 147 | 14.4 | 24 (12.9) | 123 (14.7) |
| 18 | Lower respiratory tract infection | 134 | 13 | 34 (18.3) | 100 (11.9) |
| 19 | Dyspnoea/wheezing | 131 | 12.8 | 27 (14.5) | 104 (12.4) |
| 20 | Dental/oral | 130 | 12.7 | 28 (15) | 102 (12.2) |
ICD-10, International Statistical Classification of Diseases, 10th revision.