Table 3

Twenty regression analyses showing the independent associations of gender, level of intellectual disabilities, Down syndrome and age, with the top 20 physical health conditions (ORs (95% CIs))

Physical health conditionGenderLevel of disabilityDown syndromeAge
Ref=MaleMildModerateSevereProfoundRef: without16–2425–3435–4445–5455–6465+
Vision0.79
(0.61 to 1.02)
Ref 1.12
(0.81 to 1.55)
1.80
(1.27 to 2.57)
2.57
(1.78 to 3.70)
1.10
(0.79 to 1.53)
Ref0.83
(0.51 to 1.35)
1.11
(0.71 to 1.73)
1.05
(0.67 to 1.65)
0.88
(0.55 to 1.42)
0.77
(0.43 to 1.36)
Obesity 1.34 
(1.03 to 1.73)
Ref 0.78
(0.56 to 1.08)
0.65
(0.46 to 0.94)
0.30
(0.19 to 0.45)
2.06 
(1.47 to 2.88)
Ref 1.35 
(0.81 to 2.24)
1.06 
(0.66 to 1.70)
1.78 
(1.11 to 2.84)
0.96 
(0.58 to 1.60)
1.21 
(0.67 to 2.18)
Epilepsy1.04
(0.79 to 1.38)
Ref 1.57
(1.09 to 2.3)
1.78
(1.21 to 2.62)
4.49
(3.06 to 6.65)
0.21
(0.13 to 0.34)
Ref 1.74
(1.02 to 2.97)
1.68
(1.02 to 2.75)
1.23
(0.74 to 2.02)
1.02
(0.60 to 1.74)
0.68
(0.35 to 1.30)
Constipation 1.50
(1.14 to 1.97)
Ref 1.26
(0.88 to 1.82)
1.85
(1.27 to 2.70)
4.30
(2.95 to 6.28)
0.56
(0.38 to 0.82)
Ref1.38
(0.81 to 2.34)
1.18
(0.72 to 1.94)
1.59
(0.97 to 2.59)
1.13
(0.67 to 1.92)
1.15
(0.62 to 2.15)
Ataxic/
gait disorder
1.23
(0.92 to 1.64)
Ref 2.40
(1.62 to 3.56)
3.79
(2.51 to 5.67)
6.66
(4.42 to 10.03)
0.40
(0.26 to 0.62)
Ref1.43
(0.81 to 2.54)
1.37
(0.80 to 2.34)
1.78
(1.05 to 3.03)
1.59
(0.90 to 2.78)
2.59
(1.36 to 4.91)
Hearing0.97
(0.73 to 1.30)
Ref0.94
(0.65 to 1.36)
1.08
(0.73 to 1.61)
0.86
(0.56 to 1.32)
2.46
(1.74 to 3.49)
Ref 0.71
(0.39 to 1.29)
0.91
(0.54 to 1.54)
1.22
(0.73 to 2.05)
1.37
(0.80 to 2.38)
4.59
(2.49 to 8.46)
Nail disorder1.24
(0.92 to 1.66)
Ref1.01
(0.69 to 1.49)
1.05
(0.70 to 1.59)
0.9
(0.59 to 1.39)
1.24
(0.85 to 1.80)
Ref 1.95
(1.02 to 3.73)
1.70
(0.92 to 3.12)
2.92
(1.61 to 5.29)
1.79
(0.94 to 3.41)
2.41
(1.20 to 4.94)
Epidermal thickening 1.83
(1.34 to 2.50)
Ref 1.49
(1 to 2.21)
1.23
(0.79 to 1.92)
1.32
(0.85 to 2.07)
2.74
(1.91 to 3.93)
Ref 2.87
(1.40 to 5.86)
2.29
(1.16 to 4.53)
2.94
(1.49 to 5.79)
3.25
(1.60 to 6.59)
2.34
(1.01 to 5.40)
Cerebral palsy0.86
(0.61 to 1.22)
Ref 2.38
(1.41 to 4.04)
4.10
(2.43 to 6.86)
9.86
(6.02 to 16.15)
0.15
(0.07 to 0.32)
Ref1.62
(0.86 to 3.06)
1.17
(0.63 to 2.14)
1.25
(0.68 to 2.29)
0.84
(0.43 to 1.63)
0.63
(0.27 to 1.47)
Osteoporosis 2.34
(1.64 to 3.32)
Ref 1.68
(1.01 to 2.82)
2.67
(1.61 to 4.44)
9.66
(6.01 to 15.54)
0.22
(0.11 to 0.43)
Ref1.59
(0.77 to 3.26)
2.11
(1.08 to 4.13)
1.55
(0.78 to 3.08)
2.40
(1.20 to 4.84)
2.85
(1.30 to 6.27)
Fungal infection0.85
(0.60 to 1.20)
Ref 0.66
(0.43 to 1.03)
0.76
(0.48 to 1.20)
0.39
(0.22 to 0.69)
1.68
(1.11 to 2.53)
Ref 9.00
(3.09 to 26.20)
3.77
(1.29 to 10.99)
8.22
(2.89 to 23.39)
6.40
(2.18 to 18.79)
5.33
(1.66 to 17.11)
Hypertension0.93
(0.65 to 1.33)
Ref 0.65
(0.42 to 1.00)
0.43
(0.25 to 0.72)
0.31
(0.17 to 0.57)
0.22
(0.10 to 0.46)
Ref 2.11
(0.78 to 5.66)
2.52
(1.01 to 6.30)
4.49
(1.83 to 10.98)
5.31
(2.15 to 13.16)
7.74
(2.99 to 19.99)
Bone deformity1.31
(0.92 to 1.85)
Ref 1.37
(0.85 to 2.21)
1.27
(0.76 to 2.13)
2.96
(1.87 to 4.70)
1.03
(0.65 to 1.64)
Ref 1.22
(0.6 to 2.47)
1.01
(0.52 to 1.98)
1.58
(0.83 to 3.02)
1.53
(0.77 to 3.04)
2.06
(0.95 to 4.47)
Musculoskeletal 1.89
(1.32 to 2.70)
Ref 0.54
(0.35 to 0.85)
0.45
(0.27 to 0.74)
0.16
(0.07 to 0.34)
1.14
(0.73 to 1.79)
Ref2.35
(0.99 to 5.57)
2.08
(0.92 to 4.70)
3.10
(1.39 to 6.95)
3.22
(1.40 to 7.41)
2.31
(0.90 to 5.96)
Eczema0.95
(0.66 to 1.35)
Ref0.62
(0.38 to 1.0)
0.89
(0.55 to 1.45)
0.92
(0.57 to 1.50)
1.70
(1.12 to 2.59)
Ref1.04
(0.55 to 1.97)
0.74
(0.40 to 1.36)
0.890
(0.49 to 1.62)
0.71
(0.36 to 1.38)
0.81
(0.36 to 1.81)
Gastro-oesophageal reflux disorder1.31
(0.91 to 1.87)
Ref 0.85
(0.5 to 1.45)
1.40
(0.84 to 2.35)
3.36
(2.13 to 5.29)
0.95
(0.59 to 1.53)
Ref1.05
(0.49 to 2.22)
1.63
(0.84 to 3.18)
1.80
(0.92 to 3.49)
1.22
(0.58 to 2.55)
1.21
(0.50 to 2.93)
Dysphagia 1.46
(1.01 to 2.12)
Ref 2.35
(1.30 to 4.25)
3.58
(1.99 to 6.44)
10.50
(6.13 to 17.98)
0.96
(0.58 to 1.59)
Ref1.24
(0.61 to 2.50)
1.17
(0.60 to 2.27)
1.04
(0.53 to 2.03)
1.39
(0.69 to 2.8)
0.94
(0.38 to 2.32)
Lower respiratory tract infection0.9
(0.62 to 1.30)
Ref 0.78
(0.46 to 1.32)
0.76
(0.43 to 1.34)
2.51
(1.58 to 3.99)
1.87
(1.20 to 2.92)
Ref0.68
(0.35 to 1.32)
0.64
(0.35 to 1.17)
0.63
(0.34 to 1.17)
0.63
(0.32 to 1.23)
0.78
(0.34 to 1.78)
Dyspnoea 2.07
(1.42 to 3.03)
Ref 0.95
(0.59 to 1.52)
1.03
(0.63 to 1.69)
0.38
(0.19 to 0.75)
1.12
(0.70 to 1.8)
Ref1.25
(0.54 to 2.88)
1.29
(0.60 to 2.77)
2.43
(1.16 to 5.06)
1.30
(0.57 to 2.94)
2.30
(0.98 to 5.44)
Dental health0.90
(0.62 to 1.31)
Ref0.88
(0.54 to 1.42)
1.15
(0.70 to 1.88)
0.65
(0.3 to 1.16)
1.28
(0.80 to 2.04)
Ref1.90
(0.92 to 3.94)
0.97
(0.47 to 2.01)
1.51
(0.75 to 3.04)
1.21
(0.56 to 2.58)
1.31
(0.54 to 3.15)
  • Numbers in bold are significant results.