Summary of risk of bias analysis for each included study
| Author, year | Components of risk of bias | Summary | Comments on high-risk components | ||||||
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | |||
| Agergaard et al)31 | L | U | L | L | U | L | L | High (0) Unclear (2) Low (5) | N/A |
| Bunout et al 32 | L | U | U | U | U | U | U | High (0) Unclear (6) Low (1) | N/A |
| Drey et al 33 | L | L | U | U | L | L | U | High (0) Unclear (3) Low (4) | N/A |
| Gianoudis et al 34 | L | U | U | U | H | L | L | High (1) Unclear (3) Low (3) | One high-risk component, 5 ITT analysis used, but no data entered for participants with missing data |
| Jessup et al 35 | L | U | U | U | U | U | L | High (0) Unclear (5) Low (2) | N/A |
| Uusi-Rasi et al 21 | L | U | U | U | U | L | L | High (0) Unclear (4) Low (3) | N/A |
| Verschueren et al 36 | L | U | U | U | U | L | L | High (0) Unclear (4) Low (3) | N/A |
ITT, intention to treat; N/A, not available.