HRs of myocardial infarction for individuals diagnosed with atopic dermatitis from 1977 to 1983 in Denmark, compared with a general population cohort matched for gender and birth-year
| Comparison with general population cohort | ||
|---|---|---|
| Characteristics | Crude HR (95% CI) | Adjusted HR (95% CI)* |
| Overall | 1.79 (1.25 to 2.57) | 1.74 (1.21 to 2.49) |
| Male | 2.03 (1.32 to 3.12) | 2.01 (1.31 to 3.08) |
| Female | 1.39 (0.72 to 2.69) | 1.28 (0.66 to 2.48) |
| Age at AD diagnosis (years) | ||
| 0–19 | 1.93 (0.75 to 5.01) | 1.64 (0.62 to 4.33) |
| 20– | 1.76 (1.20 to 2.60) | 1.76 (1.20 to 2.60) |
| Number of AD hospital contacts | ||
| 2–4 | 1.74 (1.13 to 2.67) | 1.71 (1.11 to 2.64) |
| 5–9 | 1.86 (0.87 to 3.95) | 1.69 (0.79 to 3.63) |
| ≥10 | 2.00 (0.58 to 6.92) | 1.95 (0.55 to 6.91) |
| Use of systemic AD treatment† | ||
| No | 1.62 (1.04 to 2.51) | 1.58 (1.02 to 2.45) |
| Yes | 2.38 (1.26 to 4.50) | 2.40 (1.27 to 4.54) |
| Asthma or rhinitis | ||
| No | 1.76 (1.17 to 2.64) | 1.72 (1.14 to 2.59) |
| Yes | 1.97 (0.92 to 4.21) | 1.73 (0.80 to 3.74) |
*Adjusted for: birth-year categories, gender, educational level and history of diabetes, hypertension, hyperlipidaemia or stroke.
†For the part (4639 patients with AD) of the study population still at risk of incident MI by 1995, when the prescription data were first available.
AD, atopic dermatitis; MI, myocardial infarction.