Base case cost-effectiveness results for different durations of effect: per-patient average costs and effects
| Modelled duration of effect | ||||
|---|---|---|---|---|
| 1 year | 2 years | 5 years | Lifetime (permanent) effect | |
| Control arm NHS costs | £6595 | £6617 | £6608 | £6602 |
| Intervention arm NHS costs | £6726 | £6741 | £6714 | £6657 |
| Control arm QALYs | 8.573 | 8.573 | 8.573 | 8.572 |
| Intervention arm QALYs | 8.584 | 8.586 | 8.589 | 8.598 |
| Incremental costs (95% CI) | £131 (£125 to 138) | £124 (£118 to 130) | £107 (101 to 112) | £55 (49 to 61) |
| Incremental QALYs (95% CI) | 0.011 (0.011 to 0.011) | 0.013 (0.012 to 0.013) | 0.016 (0.016 to 0.017) | 0.026 (0.026 to 0.027) |
| ICER | £11 776 | £9886 | £6477 | £2091 |
| Probability cost-effective at £20 000 threshold | 0.74 | 0.84 | 0.95 | 0.99 |
| Probability cost-effective at £30 000 threshold | 0.87 | 0.93 | 0.99 | 1.00 |
| NMB at threshold of £20 000 (95% CI) | £92 (−172 to 352) | £127 (−144 to 382) | £223 (−153 to 468) | £472 (197 to 728) |
CE, cost-effectiveness; ICER, incremental cost-effectiveness ratio; NMB, net monetary benefit; QALYs, quality-adjusted life years.