Final conclusion based on reported analyses of time-to-event or binary outcomes
| Final conclusion: significant? | |||
|---|---|---|---|
| Outcome | Studies (n) | Yes | No |
| (I) Published studies | 11 | ||
| Overall survival | 3 | 0 | 3 |
| Cancer-specific survival | 2 | 1 | 1 |
| Recurrence-free survival | 2 | 1 | 1 |
| Progression-free survival | 4 | 2 | 2 |
| Combined end point | 2 | 1 | 1 |
| Binary end point (recurrence, progression) | 4 | 2 | 2 |
| Total number of available results | 17 | 7 | 10 |
| (II) Unpublished studies | 5 | ||
| Recurrence | 4 | 2 | 2 |
| Progression | 2 | 0 | 2 |
| Combined end point | 1 | 0 | 1 |
| Total number of available results | 7 | 2 | 5 |
If several results for same outcome using same set of patients within a study were available, conclusion was drawn from the analysis that is presumably least biased (eg, multivariable Cox regression).