Table 3

Sustainability of professionals’ adherence to clinical practice guidelines

Study IDAuthors’ comments in terms of sustainability of adherence to the clinical practice guideline*Sustained compared with early implementation results (100%) (yes/no)†Sustained compared with early implementation results (90%) (yes/no)‡
Ament et al22“Adherence to the guideline recommendations was sustained in four early adopter hospitals”YesYes
Benenson et al23“The observed pre pathway to post pathway differences were sustained over three years”YesYes
Cates24(Centre 1 and 2) “our approach has brought about a sustained reduction in the use of antibiotics for children with acute otitis media, and after dissemination of our findings, similar results have been replicated at centre II using deferred prescribing of antibiotics for children who are not unduly ill”YesYes
Enriquez-Puga et al25“There was a small change in the desired direction in the proportion of antidepressants prescribed according to guidelines that lasted for 24 months, although no change for antibiotics. A simple, group level educational outreach intervention, designed to take account of identified barriers to change, appears to have a small sustained effect on prescribing levels, but the effect is not consistent across different groups of drugs”Guideline 1: no
Guideline 2: yes
Guideline 1: no
Guideline 2: yes
Forsner et al26“This study suggested that the compliance to clinical guidelines, for treatment of depression and suicidal behaviour, was implemented and sustained over a two-year period after an active implementation”Guideline 1: mixed
Guideline 2: mixed
Guideline 1: mixed
Guideline 2: mixed
Gerber et al35Not mentionedNoNo
Higuchi et al27(1) “The chart audit revealed that eleven nursing care indicators related to the asthma guideline recommendations showed a mixed pattern of sustainability”
(2) Not mentioned
Guideline 1: mixed
Guideline 2: mixed
Guideline 1: mixed
Guideline 2: mixed
Kelly28“The study demonstrated a significant and sustained change in analgesia administration practices away from the intramuscular (IM) route in favour of the IV route”NANA
Knops et al29(1) Not mentioned
(2) Not mentioned
Guideline 1: yes
Guideline 2: no
Guideline 1: yes
Guideline 2: no
Loszadi et al30Not mentionedYesYes
McLaws et al31Not mentionedNoYes
Stéphan et al32“One of the most important results of our intervention is its sustained impact. In particular, the frequency of catheter use decreased in the operating room not only immediately after guideline implementation, but also could be observed 2 years later”NoYes
Wakefield et al33Not mentionedNoNa
Williams et al34Not mentionedYesyes
  • *Citations of the authors of reviewed papers about the sustainability of adherence to the clinical practice guideline. †The same level or improved professionals’ adherence was achieved years after implementation compared with early postimplementation results (yes/no). ‡At least 90% of professionals’ adherence was achieved years after implementation, compared with early postimplementation results (yes/no).

  • Mixed, the overall professionals’ adherence was not presented, and both sustained and not sustained levels of professionals’ adherence to clinical practice guideline recommendations were achieved in the late post-implementation phase compared to early post-implementation results; NA, not applicable as the early post-implementation results were not measured.