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  • CRISTAL: protocol for a cluster randomised, crossover, non-inferiority trial of aspirin compared to low molecular weight heparin for venous thromboembolism prophylaxis in hip or knee arthroplasty, a registry nested study

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Surgery
Protocol
CRISTAL: protocol for a cluster randomised, crossover, non-inferiority trial of aspirin compared to low molecular weight heparin for venous thromboembolism prophylaxis in hip or knee arthroplasty, a registry nested study

Authors

  • Verinder Singh Sidhu CRISTAL Study Group, Whitlam Orthopaedic Research Centre, Ingham Institute for Applied Medical Research, University of New South Wales South Western Sydney Clinical School, Liverpool, New South Wales, Australia PubMed articlesGoogle scholar articles
  • Steven E Graves Australian Orthopaedic Association National Joint Replacement Registry, Adelaide, South Australia, Australia PubMed articlesGoogle scholar articles
  • Rachelle Buchbinder Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, AustraliaMonash Department of Clinical Epidemiology, Cabrini Institute, Melbourne, Victoria, Australia PubMed articlesGoogle scholar articles
  • Justine Maree Naylor CRISTAL Study Group, Whitlam Orthopaedic Research Centre, Ingham Institute for Applied Medical Research, University of New South Wales South Western Sydney Clinical School, Liverpool, New South Wales, Australia PubMed articlesGoogle scholar articles
  • Nicole L Pratt School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South Australia, Australia PubMed articlesGoogle scholar articles
  • Richard S de Steiger Department of Surgery, Epworth Healthcare, University of Melbourne, Melbourne, Victoria, Australia PubMed articlesGoogle scholar articles
  • Beng H Chong Department of Haematology, Saint George and Sutherland Clinical School, University of New South Wales, Sydney, New South Wales, Australia PubMed articlesGoogle scholar articles
  • Ilana N Ackerman Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia PubMed articlesGoogle scholar articles
  • Sam Adie Faculty of Medicine, Saint George and Sutherland Clinical School, University of New South Wales, Sydney, New South Wales, Australia PubMed articlesGoogle scholar articles
  • Anthony Harris Monash University Centre for Health Economics, Caufield, Victoria, Australia PubMed articlesGoogle scholar articles
  • Amber Hansen CRISTAL Study Group, Whitlam Orthopaedic Research Centre, Ingham Institute for Applied Medical Research, University of New South Wales South Western Sydney Clinical School, Liverpool, New South Wales, Australia PubMed articlesGoogle scholar articles
  • Maggie Cripps CRISTAL Study Group, Whitlam Orthopaedic Research Centre, Ingham Institute for Applied Medical Research, University of New South Wales South Western Sydney Clinical School, Liverpool, New South Wales, Australia PubMed articlesGoogle scholar articles
  • Michelle Lorimer South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia PubMed articlesGoogle scholar articles
  • Steve Webb Department of Intensive Care, St John of God Hospital, Subiaco, Western Australia, AustraliaDepartment of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Austria PubMed articlesGoogle scholar articles
  • Ornella Clavisi Musculoskeletal Australia, Melbourne, Victoria, Australia PubMed articlesGoogle scholar articles
  • Elizabeth C Griffith South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia PubMed articlesGoogle scholar articles
  • Durga Anandan Australian Orthopaedic Association National Joint Replacement Registry, Adelaide, South Australia, Australia PubMed articlesGoogle scholar articles
  • Grace O'Donohue Australian Orthopaedic Association National Joint Replacement Registry, Adelaide, South Australia, Australia PubMed articlesGoogle scholar articles
  • Thu-Lan Kelly School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South Australia, Australia PubMed articlesGoogle scholar articles
  • Ian A Harris CRISTAL Study Group, Whitlam Orthopaedic Research Centre, Ingham Institute for Applied Medical Research, University of New South Wales South Western Sydney Clinical School, Liverpool, New South Wales, AustraliaInstitute for Musculoskeletal Health, The University of Sydney School of Public Health, Sydney, New South Wales, Australia PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Verinder Singh Sidhu; verinder.s.sidhu{at}gmail.com
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Citation

Sidhu VS, Graves SE, Buchbinder R, et al
CRISTAL: protocol for a cluster randomised, crossover, non-inferiority trial of aspirin compared to low molecular weight heparin for venous thromboembolism prophylaxis in hip or knee arthroplasty, a registry nested study
BMJ Open 2019;9:e031657. doi: 10.1136/bmjopen-2019-031657

Publication history

  • Received May 15, 2019
  • Revised September 19, 2019
  • Accepted October 7, 2019
  • First published November 6, 2019.
Online issue publication 
November 06, 2019
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© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.