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Informing efficient randomised controlled trials: exploration of challenges in developing progression criteria for internal pilot studies

Authors

  • Kerry N L Avery Medical Research Council ConDuCT-II Hub for Trials Methodology Research, School of Social and Community Medicine, University of Bristol, Bristol, UK PubMed articlesGoogle scholar articles
  • Paula R Williamson Medical Research Council North West Hub for Trials Methodology Research, Department of Biostatistics, University of Liverpool, Liverpool, UK PubMed articlesGoogle scholar articles
  • Carrol Gamble Medical Research Council North West Hub for Trials Methodology Research, Department of Biostatistics, University of Liverpool, Liverpool, UK PubMed articlesGoogle scholar articles
  • Elaine O'Connell Francischetto Medical Research Council ConDuCT-II Hub for Trials Methodology Research, School of Social and Community Medicine, University of Bristol, Bristol, UK PubMed articlesGoogle scholar articles
  • Chris Metcalfe Medical Research Council ConDuCT-II Hub for Trials Methodology Research, School of Social and Community Medicine, University of Bristol, Bristol, UK PubMed articlesGoogle scholar articles
  • Peter Davidson National Institute for Health Research Evaluation, Trials and Studies Coordinating Centre, University of Southampton, Southampton, UK PubMed articlesGoogle scholar articles
  • Hywel Williams Centre of Evidence-Based Dermatology, University of Nottingham, Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK PubMed articlesGoogle scholar articles
  • Jane M Blazeby Medical Research Council ConDuCT-II Hub for Trials Methodology Research, School of Social and Community Medicine, University of Bristol, Bristol, UK Division of Surgery, Head and Neck, University Hospitals Bristol NHS Foundation Trust, Bristol, UK PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Kerry NL Avery; kerry.avery{at}bristol.ac.uk
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Citation

Avery KNL, Williamson PR, Gamble C, et al
Informing efficient randomised controlled trials: exploration of challenges in developing progression criteria for internal pilot studies
BMJ Open 2017;7:e013537. doi: 10.1136/bmjopen-2016-013537

Publication history

  • Received July 19, 2016
  • Revised December 19, 2016
  • Accepted January 19, 2017
  • First published February 17, 2017.
Online issue publication 
October 26, 2017
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Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/