RT Journal Article SR Electronic T1 Pulmonary veno-occlusive disease: atypical presentation with unexplained exertional dyspnoea and hypoxaemia JF BMJ Case Reports JO BMJ Case Reports FD BMJ Publishing Group Ltd SP e265170 DO 10.1136/bcr-2025-265170 VO 18 IS 4 A1 Hatipoğlu, Umur Şevket A1 Smith, Michael A1 Arrossi, Andrea V A1 Tonelli, Adriano R YR 2025 UL http://casereports.bmj.com/content/18/4/e265170.abstract AB Pulmonary veno-occlusive disease is an uncommon condition that typically presents with moderate to severe pulmonary hypertension and characteristic imaging abnormalities. We report two patients who presented with severe hypoxaemia and low diffusion capacity without pulmonary hypertension and classical imaging findings. Pulmonary venoocclusive disease should be included in the differential diagnosis of unexplained hypoxemia.