Article Text
PDF
Abstract
Amlodipine, a widely used antihypertensive medication, can cause serious complications in overdose, including hypotension, bradycardia, non-cardiogenic pulmonary oedema (NCPO) and death. This report describes a young adult woman who ingested 100 mg of amlodipine in a polypharmacy suicide attempt. Although she initially stabilised, she unexpectedly developed delayed NCPO 3 days post ingestion, requiring intubation and intensive care unit readmission. She recovered fully with supportive care and was discharged in good health. This case highlights the importance of prolonged monitoring and vigilance in managing long-acting calcium channel blocker overdoses, even when the initial clinical response appears satisfactory.
- Cardiovascular system
- Poisoning
- Adult intensive care
- Pharmacokinetics
- Toxicology
Statistics from Altmetric.com
Footnotes
Contributors LDZ was the principal author of this case report. He was involved in patient management and took primary responsibility for writing the case report. AGP, as the consultant, provided expertise on patient management and offered guidance and editorial suggestions throughout the preparation of the final manuscript. LDZ is the guarantor, ensuring the accuracy and integrity of the case report.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.