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Gastroenterology
Systemic lupus erythematosus unmasked: intestinal pseudo-obstruction as the first presentation
  1. Dandi Kranthi1,
  2. Debabrata Banerjee2,
  3. Amol Dahale2 and
  4. Abhijeet Bhausaheb Karad2
  1. 1Medical Gastroenterology, Dr DY Patil Medical College, Hospital & Research Center, Dr DY Patil Vidyapeeth (Deemed to be University), Pimpri, Pune, Maharshtra, India
  2. 2Medical Gastroenterology, Dr DY Patil Medical College, Hospital & Research Center, Dr. DY Patil Vidyapeeth (Deemed to be University), Pimpri, Pune, Maharashtra, India
  1. Correspondence to Dr Debabrata Banerjee; drdbanerjee{at}gmail.com

Abstract

Systemic lupus erythematosus (SLE) is an autoimmune inflammatory condition with a varied clinical presentation. It can involve multiple organ systems and has the potential to impact any part of the gastrointestinal tract. Intestinal pseudo-obstruction (IPO) is a rare yet severe gastrointestinal manifestation of SLE. Two-thirds of SLE patients with IPO present with concomitant hydroureteronephrosis. This report details the case of a young woman who presented with IPO as the initial manifestation of SLE. The presence of proteinuria with bilateral hydroureteronephrosis in this patient with IPO prompted a trail of investigations that led to the diagnosis of SLE. This diagnosis mitigated the need for surgery, as the patient responded to immunosuppressive therapy.

  • Systemic lupus erythematosus
  • Proteinurea
  • Small intestine

https://doi.org/10.1136/bcr-2024-263491

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    Footnotes

    • Contributors DK is the guarantor. All authors (DK, AD, ABK and DB) were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms, critical revision for important intellectual content and gave final approval of the manuscript.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.