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Epidural lymphoma: a rare presentation of extranodal disease
  1. Vijay Alexander1,
  2. Sharon Anbumalar Lionel2,
  3. George Abraham Ninan3 and
  4. Tina George3
  1. 1Department of Hepatology, Christian Medical College, Vellore, India
  2. 2Department of Haematology, Christian Medical College, Vellore, India
  3. 3Department of Medicine, Christian Medical College, Vellore, India
  1. Correspondence to Dr Vijay Alexander; vijayalexander{at}cmcvellore.ac.in

Abstract

Extranodal involvement in lymphomas is well-documented in the literature. However, certain anatomical sites, such as the epidural space, are rarely affected by lymphoproliferative neoplasms. When lymphomas are confined to the epidural space without other recognisable sites of involvement at diagnosis, they are classified as primary spinal epidural lymphoma. We report the case of a man in his early 30s who presented with lower back pain and progressive quadriparesis. Imaging revealed an extradural mass extending from the sixth to the tenth thoracic vertebrae, with lateral extension into the extrapleural space. A biopsy confirmed diffuse large B-cell lymphoma, and the patient was started on combination chemotherapy.

  • Magnetic Resonance Imaging
  • Spinal cord
  • Oncology

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Footnotes

  • Contributors VA, TG, GAN and SAL were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms, critical revision for important intellectual content and gave the final approval of the manuscript. The patient is not one of the authors of this manuscript. All authors gave final approval of the manuscript. VA is the guarantor for submission.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.