Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disorder with diverse clinical presentations, including gastrointestinal involvement. We report a case of a young woman with a decade-long history of SLE presenting with recurrent abdominal pain, vomiting and weight loss. Initially suspected to be pancreatitis, further investigations revealed gastric nodules and the biopsy was suggestive of neuroendocrine tumour. This case underscores the importance of considering rare causes of abdominal pain in patients with SLE and vigilance for potential malignancies. The association between SLE and gastric neuroendocrine tumours remains poorly understood, emphasising the need for further exploration. This case contributes to the growing literature on rare gastrointestinal manifestations in SLE, prompting clinicians to maintain a wide differential diagnoses for abdominal symptoms in this patient population.