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Paediatrics
Recurrent haemorrhagic venous infarct in a patient with sickle cell disease
  1. Alyaa Al Ali1,
  2. Sulaima Mhd Taji2,
  3. Fatmah Al Zeyoudi3 and
  4. Musaab Ramsi4
  1. 1Paediatric critical Care Medicine, Sheikh Khalifa Medical City, Abu Dhabi, Abu Dhabi, UAE
  2. 2Pediatric, Shaikh Khalifa Medical City, Abu Dhabi, Abu Dhabi, UAE
  3. 3Radiology, Shaikh Khalifa Medical City, Abu Dhabi, Abu Dhabi, UAE
  4. 4Pediatric Critical Care, Shaikh Khalifa Medical City, Abu Dhabi, UAE
  1. Correspondence to Dr Alyaa Al Ali; alalali.uae{at}gmail.com

Abstract

Cerebrovascular accidents are uncommon but devastating complications of sickle cell disease (SCD). Notably, cerebral sinovenous thrombosis is rarely reported in SCD and poses a therapeutic dilemma regarding anticoagulation. Herein, we describe a challenging case of a patient with sickle thalassaemia admitted to the hospital with recurrent haemorrhagic infarct secondary to cerebral sinus thrombosis. The patient was successfully treated with anticoagulation without neurological deficit. No embolic or other thrombotic aetiology was found, and the stroke was presumed due to sickle cell disease, leading to a hypercoagulable state. Our case report highlights the value of early recognition of this rare but potentially life-threatening condition in SCD, considers other options of anticoagulation therapy and emphasises the importance of close multidisciplinary follow-up particularly post hospital discharge.

  • Haematology (incl blood transfusion)
  • Paediatric intensive care
  • Stroke

https://doi.org/10.1136/bcr-2024-260915

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    Footnotes

    • X @picu_ae, @Musaabalramsi

    • Contributors The following authors were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms, and critical revision for important intellectual content: AAA, SMT, FAZ and MR. The following authors gave final approval of the manuscript: AAA, SMT, FAZ and MR.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.