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Oncology
Gallbladder carcinoma presenting with disseminated bony metastasis
  1. Amitabh Kumar Upadhyay1,
  2. Shashank Shekhar2,
  3. Abhishek Kumar3 and
  4. Somshankar Chowdhury4
  1. 1Medical Oncology, Tata Main Hospital, Jamshedpur, Jharkhand, India
  2. 2Medical Oncology, Meherbai Tata Memorial Hospital, Jamshedpur, Jharkhand, India
  3. 3Nuclear Medicine, Tata Main Hospital, Jamshedpur, Jharkhand, India
  4. 4Pathology, Meherbai Tata Memorial Hospital, Jamshedpur, Jharkhand, India
  1. Correspondence to Dr Amitabh Kumar Upadhyay; dramit1111{at}gmail.com

Abstract

Gallbladder cancer (GBC) is the 23rd most common cancer worldwide and one of the three leading cancers in North and Northeast India. GBC has inferior outcomes due to its advanced presentation and poor response to chemotherapy. The approximate 5-year survival rate for metastatic GBC is less than 5%, with a median survival of around 6 months. Distant metastases from GBC to the bones happen in the later part of the natural history of the disease. Presentation with bony metastasis is infrequent, and less than 25 cases have been reported. Our case was an elderly man in his 70s who presented with back pain and, on workup, was detected to have adenocarcinoma of the gall bladder with disseminated lytic bony metastasis without any visceral metastasis. This case describes the natural history of such cases and discusses the role of bone scan or fluorodeoxyglucose positron emission tomography in the workup for GBC.

  • Carcinogenesis
  • Chemotherapy
  • Screening (oncology)
  • Pain
  • Incidence

https://doi.org/10.1136/bcr-2023-257753

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    Footnotes

    • Contributors AKU, SS, AK and SC were responsible for drafting the text, sourcing and editing the clinical images, investigating the results, drawing the original diagrams and algorithms, and critical revision for important intellectual content. AKU, SS, AK and SC gave final approval of the manuscript.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.