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Case Reports: Rare disease
Unusual non-infectious cause of meningitis
  1. Pradeep Shrestha,
  2. Buddhi Paudyal,
  3. Lucky Sharma and
  4. Keshav Raj Sigdel
  1. Rheumatology Unit, Department of Internal Medicine, Patan Academy of Health Sciences, Lalitpur, Nepal
  1. Correspondence to Dr Lucky Sharma; luckysharma{at}pahs.edu.np

Abstract

Meningitis, though commonly caused by various infectious agents, may also have non-infectious aetiologies. The clinical presentation, however may be identical to infectious meningitis. We present a case of a female in her 50s who presented with fever, headache, vomiting and neck rigidity. She had features of inflammatory polyarthritis, cold sensitivity, puffy digits, alopecia and easy fatigability. No evidence of infection was found, and serological features consistent with mixed connective tissue disease (MCTD) were revealed, which led to the diagnosis of MCTD-related aseptic meningitis.

  • rheumatology
  • connective tissue disease

https://doi.org/10.1136/bcr-2023-255981

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    Footnotes

    • Contributors PS, BP, LS and KRS were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms and critical revision for important intellectual content. BP gave final approval of the manuscript.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.