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Rare disease
CASE REPORT
Nephrotic syndrome without kidney injury revealing intravascular large B cell lymphoma
  1. Lucie Pothen1,
  2. Selda Aydin2,
  3. Alessandra Camboni2 and
  4. Philippe Hainaut1
  1. 1 Service de Médecine interne et Maladies Infectieuses, Cliniques Universitaires Saint-Luc, Bruxelles, Belgium
  2. 2 Service d’Anatomie Pathologique, Cliniques Universitaires Saint-Luc, Bruxelles, Belgium
  1. Correspondence to Dr Lucie Pothen, lucie.pothen{at}uclouvain.be

Abstract

We describe the case of a 64-year-old woman admitted for fever of unknown origin, who developed nephrotic syndrome during hospitalisation and pulmonary infiltrates. Renal biopsy disclosed intracapillary glomerular invasion by intravascular large B cell lymphoma. Clinical and biological evolution was favourable after rituximab, cyclophosphamide, doxorubicine, vincristine and prednisone (R-CHOP) treatment and autologous stem cell transplant. Two years after diagnosis the patient was considered in remission.

  • haematology (incl blood transfusion)
  • nephrotic syndrome

https://doi.org/10.1136/bcr-2019-229359

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    Footnotes

    • Contributors LP and PH were in charge of patient diagnosis. SA and AC contributed to diagnosis. LP wrote the report. SA and AC created the figure and the legend. All authors reviewed the report.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.

    • Patient consent for publication Obtained.