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  • Isolated primary maxillary sinus esthesioneuroblastoma presenting as idiopathic syndrome of inappropriate antidiuretic hormone

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Unusual presentation of more common disease/injury
CASE REPORT
Isolated primary maxillary sinus esthesioneuroblastoma presenting as idiopathic syndrome of inappropriate antidiuretic hormone
  1. Eugene Wong1,
  2. Siamak Choroomi1,
  3. Carsten E Palme1 and
  4. Narinder Pal Singh2
  1. 1 Department of Otolaryngology, University of Sydney Westmead Clinical School, Sydney, New South Wales, Australia
  2. 2 Department of Otolaryngology, Head and Neck Surgery, Westmead Hospital, Sydney, New South Wales, Australia
  1. Correspondence to Dr Eugene Wong, eugene.hl.wong{at}gmail.com

Abstract

Esthesioneuroblastoma is an uncommon tumour, and isolated primary involvement of the maxillary sinus is exceedingly rare. Esthesioneuroblastoma has infrequently been reported as a source of paraneoplastic ectopic hormone production. We report a case of isolated primary maxillary esthesioneuroblastoma, presenting as idiopathic syndrome of inappropriate antidiuretic hormone (SIADH). A 17-year-old girl presented with symptoms consistent with SIADH and no sino-nasal symptoms. MRI to exclude pituitary tumour revealed an isolated lesion of the right maxillary sinus. Biopsy demonstrated esthesioneuroblastoma. The lesion was removed endoscopically as a single en bloc specimen. Following resection, the sodium level returned to normal. This is only the third report in the literature of a primary maxillary esthesioneuroblastoma presenting as SIADH.

  • ear, nose and throat/otolaryngology
  • metabolic disorders

https://doi.org/10.1136/bcr-2018-228666

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    Footnotes

    • Contributors All authors (EW, SC, CEP, NPS) contributed to the conception and design, acquisition of data as well as analysis and interpretation of data; drafting the article or revising it critically for important intellectual content; final approval of the version published; agreement to be accountable for the article; and ensure that all questions regarding the accuracy or integrity of the article are investigated and resolved.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.

    • Patient consent for publication Obtained.