Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn’s disease and leads to impaired CFB cleavage and phagocytosis
Marzieh Akhlaghpour, Talin Haritunians, Shyam K More, Lisa S Thomas, Dalton T Stamps, Shishir Dube, Dalin Li, Shaohong Yang, Carol J Landers, Emebet Mengesha, Hussein Hamade, Ramachandran Murali, Alka A Potdar, Andrea J Wolf, Gregory J Botwin, Michelle Khrom, International IBD Genetics Consortium, Ashwin N Ananthakrishnan, William A Faubion, Bana Jabri, Sergio A Lira, Rodney D Newberry, Robert S Sandler, R Balfour Sartor, Ramnik J Xavier, Steven R Brant, Judy H Cho, Richard H Duerr, Mark G Lazarev, John D Rioux, L Philip Schumm, Mark S Silverberg, Karen Zaghiyan, Phillip Fleshner, Gil Y Melmed, Eric A Vasiliauskas, Christina Ha, Shervin Rabizadeh, Gaurav Syal, Nirupama N Bonthala, David A Ziring, Stephan R Targan, Millie D Long, Dermot P B McGovern, Kathrin S Michelsen
Gut Nov 2023, 72 (11) 2068-2080; DOI: 10.1136/gutjnl-2023-329689
