hepatitis B

Effects of tenofovir disoproxil fumarate on intrahepatic viral burden and liver immune microenvironment in patients with chronic hepatitis B
David Z Pan, Cameron M Soulette, Abhishek Aggarwal, Dong Han, Nicholas van Buuren, Peiwen Wu, Becket Feierbach, Jaw-Town Lin, Cheng-Hao Tseng, Chi-Yi Chen, Bryan Downie, Hongmei Mo, Lauri Diehl, Li Li, Simon P Fletcher, Scott Balsitis, Ricardo Ramirez, Vithika Suri, Yao-Chun Hsu

Gut Apr 2025, 74 (4) 628-638; DOI: 10.1136/gutjnl-2024-332526
Quest for HBV functional cure: what have we learnt from silencing RNAs?
Norah Terrault, Anna S Lok

Gut Mar 2025, 74 (3) 340-342; DOI: 10.1136/gutjnl-2024-333763
Long-term hepatitis B surface antigen response after finite treatment of ARC-520 or JNJ-3989
Lung Yi Mak, Christine I Wooddell, Oliver Lenz, Thomas Schluep, James Hamilton, Heather L Davis, Xianhua Mao, Wai-Kay Seto, Michael Biermer, Man-Fung Yuen

Gut Mar 2025, 74 (3) 440-450; DOI: 10.1136/gutjnl-2024-333026
Immunomodulation and entry inhibition: selgantolimod’s double punch against hepatitis B virus
Thomas Baumert, Melanie Urbanek-Quaing, Markus Cornberg

Gut Dec 2024, 73 (12) 1925-1926; DOI: 10.1136/gutjnl-2024-332679
TLR8 agonist selgantolimod regulates Kupffer cell differentiation status and impairs HBV entry into hepatocytes via an IL-6-dependent mechanism
Armando Andres Roca Suarez, Marie-Laure Plissonnier, Xavier Grand, Maud Michelet, Guillaume Giraud, Maria Saez-Palma, Anaëlle Dubois, Sarah Heintz, Audrey Diederichs, Nicolaas Van Renne, Thomas Vanwolleghem, Stephane Daffis, Li Li, Nikita Kolhatkar, Yao-Chun Hsu, Jeffrey J Wallin, Audrey H Lau, Simon P Fletcher, Michel Rivoire, Massimo Levrero, Barbara Testoni, Fabien Zoulim

Gut Dec 2024, 73 (12) 2012-2022; DOI: 10.1136/gutjnl-2023-331396
Non-linear association of baseline viral load with on-treatment hepatocellular carcinoma risk in chronic hepatitis B: still needs further discussion
Taiyu He, Dazhi Zhang

Gut Nov 2024, 73 (11) e28; DOI: 10.1136/gutjnl-2023-331443
High accuracy model for HBsAg loss based on longitudinal trajectories of serum qHBsAg throughout long-term antiviral therapy
Rong Fan, Siru Zhao, Junqi Niu, Hong Ma, Qing Xie, Song Yang, Jianping Xie, Xiaoguang Dou, Jia Shang, Huiying Rao, Qi Xia, Yali Liu, Yongfeng Yang, Hongbo Gao, Aimin Sun, Xieer Liang, Xueru Yin, Yongfang Jiang, Yanyan Yu, Jian Sun, Nikolai V Naoumov, Jinlin Hou

Gut Oct 2024, 73 (10) 1725-1736; DOI: 10.1136/gutjnl-2024-332182
Spatial transcriptomics reveals a low extent of transcriptionally active hepatitis B virus integration in patients with HBsAg loss
Xiaoqi Yu, Qiming Gong, Demin Yu, Yongyan Chen, Ying Jing, Fabien Zoulim, Xinxin Zhang

Gut May 2024, 73 (5) 797-809; DOI: 10.1136/gutjnl-2023-330577
Clinical applications of circulating HBV RNA as a potential surrogate biomarker for intrahepatic cccDNA transcriptional activity
Xiaoqi Yu, Maria Pfefferkorn, Florian van Bömmel, Xinxin Zhang, Thomas Berg

Gut Apr 2024, 73 (4) 563-566; DOI: 10.1136/gutjnl-2023-331217
New facet of CARs: HBV-specific CARs as inhibitors of virus morphogenesis and release
Eberhard Hildt, Jianming Hu

Gut Apr 2024, 73 (4) 566-567; DOI: 10.1136/gutjnl-2023-331462

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