cell signalling

TPX2 serves as a novel target for expanding the utility of PARPi in pancreatic cancer through conferring synthetic lethality
Mingming Xiao, Rong Tang, Haoqi Pan, Jing Yang, Xuhui Tong, He Xu, Yanmei Guo, Yalan Lei, Di Wu, Yubin Lei, Yamei Han, Zhilong Ma, Wei Wang, Jin Xu, Xianjun Yu, Si Shi

Gut Mar 2025, 74 (3) 410-423; DOI: 10.1136/gutjnl-2024-332782
KLHL21 suppresses gastric tumourigenesis via maintaining STAT3 signalling equilibrium in stomach homoeostasis
Xiao-Bo Huang, Qiang Huang, Mei-Chen Jiang, Qing Zhong, Hua-Long Zheng, Jia-Bin Wang, Ze-Ning Huang, Hua-Gen Wang, Zhi-Yu Liu, Yi-Fan Li, Kai-Xiang Xu, Mi Lin, Ping Li, Zhi-Hong Huang, Jian-Wei Xie, Jian-Xian Lin, Jun Lu, Jian-Wen Que, Chao-Hui Zheng, Qi-Yue Chen, Chang-Ming Huang

Gut Nov 2024, 73 (11) 1785-1798; DOI: 10.1136/gutjnl-2023-331111
High-fat diet promotes liver tumorigenesis via palmitoylation and activation of AKT
Lang Bu, Zhengkun Zhang, Jianwen Chen, Yizeng Fan, Jinhe Guo, Yaqing Su, Huan Wang, Xiaomei Zhang, Xueji Wu, Qiwei Jiang, Bing Gao, Lei Wang, Kunpeng Hu, Xiang Zhang, Wei Xie, Wenyi Wei, Ming Kuang, Jianping Guo

Gut Jul 2024, 73 (7) 1156-1168; DOI: 10.1136/gutjnl-2023-330826
SK2 channels set a signalling hub bolstering CAF-triggered tumourigenic processes in pancreatic cancer
Raphael Rapetti-Mauss, Jérémy Nigri, Camille Berenguier, Pascal Finetti, Sarah Simha Tubiana, Bonnie Labrum, Benoit Allegrini, Bernard Pellissier, Georgios Efthymiou, Zainab Hussain, Corinne Bousquet, Nelson Dusetti, François Bertucci, Hélène Guizouarn, Patricia Melnyk, Franck Borgese, Richard Tomasini, Olivier Soriani

Gut Apr 2023, 72 (4) 722-735; DOI: 10.1136/gutjnl-2021-326610
Keeping the liver fit with TREM2 during hepatic carcinogenesis
Francisco Javier Cubero

Gut Jul 2021, 70 (7) 1210-1211; DOI: 10.1136/gutjnl-2020-322638
Targeting G protein-coupled receptors for the treatment of chronic pain in the digestive system
Lena Gottesman-Katz, Rocco Latorre, Stephen Vanner, Brian L Schmidt, Nigel W Bunnett

Gut May 2021, 70 (5) 970-981; DOI: 10.1136/gutjnl-2020-321193
Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP
Rajarshi Mukherjee, Olga A Mareninova, Irina V Odinokova, Wei Huang, John Murphy, Michael Chvanov, Muhammad A Javed, Li Wen, David M Booth, Matthew C Cane, Muhammad Awais, Bruno Gavillet, Rebecca M Pruss, Sophie Schaller, Jeffery D Molkentin, Alexei V Tepikin, Ole H Petersen, Stephen J Pandol, Ilya Gukovsky, David N Criddle, Anna S Gukovskaya, Robert Sutton

Gut Aug 2016, 65 (8) 1333-1346; DOI: 10.1136/gutjnl-2014-308553
Plasticity of adult hepatocytes and readjustment of cell fate: a novel dogma in liver disease
Francisco Javier Cubero, Maria Luz Martinez-Chantar

Gut Jun 2019, 68 (6) 954-956; DOI: 10.1136/gutjnl-2019-318218
Alcohol dysregulates miR-148a in hepatocytes through FoxO1, facilitating pyroptosis via TXNIP overexpression
Mi Jeong Heo, Tae Hyun Kim, Jueng Soo You, Delia Blaya, Pau Sancho-Bru, Sang Geon Kim

Gut Apr 2019, 68 (4) 708-720; DOI: 10.1136/gutjnl-2017-315123
Jnk1 in murine hepatic stellate cells is a crucial mediator of liver fibrogenesis
Gang Zhao, Maximilian Hatting, Yulia A. Nevzorova, Jin Peng, Wei Hu, Mark V Boekschoten, Tania Roskams, Michael Muller, Nikolaus Gassler, Christian Liedtke, Roger J Davis, Francisco Javier Cubero, Christian Trautwein

Gut Jul 2014, 63 (7) 1159-1172; DOI: 10.1136/gutjnl-2013-305507

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