Table 2

Multivariate Cox regression analysis for fatal ACLF development in compensated patients

Parameter	Univariate Cox regression			Multivariate Cox regression
Parameter	P value	HR	95% CI	P value	HR	95% CI
Compensated cirrhosis
CLIF-C AD	0.002	1.175	1.061 to 1.301	0.052	1.106	0.999 to 1.224
Hb	0.008	0.692	0.527 to 0.908
Albumin	<0.001	0.220	0.095 to 0.512	0.010	0.872	0.786 to 0.967
Bilirubin	<0.001	1.454	1.193 to 1.772
IL-1α ×10⁻²	0.011	1.257	1.055 to 1.499	0.013	1.248	1.048 to 1.486
IL-1β ×10⁻²	0.253

ACLF, acute-on-chronic liver failure; AD, acute decompensation; CLIF-C, European Foundation for the study of chronic liver failure consortium; Hb, haemoglobin; IL, interleukin.