Table 3

Estimated prevalence of advanced fibrosis in 264 fatty liver subjects based on clinical prediction formulae

FormulaeCut-offn95% CI
AST/ALT ratio1.032 (12.1%)8.2% to 16.1%
APRI*0.512 (4.5%)2.0% to 7.1%
1.500 to 0
FIB-4*1.3026 (9.8%)6.3% to 13.4%
2.671 (0.4%)0 to 1.1%
NAFLD fibrosis score*−1.45543 (16.3%)0 to 20.7%
0.67600 to 0
BARD score216 (6.1%)3.2% to 8.9%
  • * The lower cut-off values had high sensitivity in excluding advanced fibrosis, while the higher cut-off values had high specificity in ruling in advanced fibrosis.

  • ALT, alanine aminotransferase; APRI, AST to platelet ratio index; AST, aspartate aminotransferase; NAFLD, non-alcoholic fatty liver disease.