Table 2

Summary of recommendations for colorectal cancer screening and surveillance high risk disease groups

High risk disease groupsScreening procedureTime of initial screenScreening procedure and intervalProcedures/yr/300,000
Colorectal cancerConsultation, CT, LFT's & ColonoscopyColonoscopy within 6 months of resection only if colon evaluation pre-op. incompleteCT Liver Scan within 2 years post-op. Colonoscopy 5 yearly until co-morbidity outweighs175
Colonic adenomas
  • Low risk

  • 1-2 adenomas, both <1 cm

Colonoscopy5 years or no surveillanceCease follow-up after negative colonoscopy
  • Intermediate risk

  • 3–4 adenomas, OR at least one adenoma ≥1 cm

Colonoscopy3 years3 yearly until 2 consecutive negative colonoscopies, then no further surveillance
  • High risk

≥5 adenomas or ≥3 with at least one ≥ 1cm
Colonoscopy1 yearAnnual colonoscopy until out of this risk group then interval colonoscopy as per intermediate risk group
Piecemeal polypectomyColonoscopy or flexi-sig (depending on polyp location)3 months—consider open surgical resection if incomplete healing of polypectomy scar
Ulcerative colitis and Crohn's colitis
  • Low risk

  • Extensive colitis with no inflammation or left sided colitis or Crohn's colitis of <50% colon

Pancolonic dye spray with targeted biopsy. If no dye spray then 2–4 random biopsies every 10 cms.10 years from onset of symptoms5 years20
  • Intermediate risk

  • Extensive colitis with mild active disease or post-inflammatory polyps or family history of colorectal cancer in a FDR <50 yrs.

3 years10
  • High risk

  • Extensive at least moderate colitis or stricture in past 5 years or dysplasia in past 5 years (declining surgery) or PSC or OLT for PSC) or colorectal cancer in a FDR <50 yrs.

1 year6
Uretero-sigmoidostomyFlexi Sig10 yrs after surgeryFlexi Sig annually3
AcromegalyColonoscopyAt 40 yrs.Colonoscopy 5 yearly1
  • CT, Computed tomography; LFT's, liver function tests; OLT, orthoptic liver transplant; PSC, primary sclerosing cholangitis.