Progression of low grade dysplasia to high grade dysplasia or cancer
| Study | Reference | Year | Country | LGD (n) | Progression to HGD/CRC (%) | Follow-up (years) |
| Bernstein review | 80 | 1994 | Various | 204 | 16 | At some time (variable study follow-up) |
| Post-Bernstein review | ||||||
| Connell | 81 | 1994 | UK | 9 | 54 | 5 |
| Lindberg | 82 | 1996 | Sweden | 37 | 35 | 20 |
| Ullman | 83 | 2002 | USA | 18 | 33 | 5 |
| Befrits | 103 | 2002 | Sweden | 60 | 3 | 10 (mean) |
| Ullman | 84 | 2003 | USA | 46 | 53 | 5 |
| Lim | 104 | 2003 | UK | 29 | 10 | 10 |
| Rutter | 56 | 2006 | UK | 36 | 39 | 5 |
CRC, colorectal cancer; LGD, low grade dysplasia; HGD, high grade dysplasia.