Multivariate analysis of overall survival and disease free survival in patients with locally advanced non-metastatic colorectal cancer
Overall survival (Hazard ratio* (95% CI)) | p Value | Disease free survival (Hazard ratio* (95% CI)) | p Value | |
---|---|---|---|---|
*Adjusted for age, sex, and tumour, node, metastases (TNM) stage (Cox proportional hazards regression). | ||||
95% CI, 95% confidence interval; MMR, mismatch repair. | ||||
MMR status (deficient/competent) | 1.02 (0.49–2.13) | 0.961 | 1.22 (0.67–2.22) | 0.508 |
Adjuvant chemotherapy (yes/no) | 1.88 (1.13–3.12) | 0.015 | 1.54 (1.04–2.29) | 0.031 |
MMR status×chemotherapy | 1.81 (1.13–2.92) | 0.014 | 1.68 (1.15–2.44) | 0.007 |