Gut: 74 (6)

Commentaries

Need for standardised approaches to human microbiome research using the example of colorectal neoplasia research (2 October, 2024)
Sarah Manning, Rashmi Sinha, Colin J Rees
Time for arginine methylation: PRMT5 inhibition to advance cholangiocarcinoma treatment (6 December, 2024)
Romain Désert, Lipika Goyal, Thomas F Baumert

Endscopy news

Detection of large flat colorectal lesions by artificial intelligence: a persistent weakness and blind spot (7 January, 2025)
Douglas K Rex, John J Guardiola, Daniel von Renteln, Yuichi Mori, Prateek Sharma, Cesare Hassan

Stomach

Original research: Construction of exosome non-coding RNA feature for non-invasive, early detection of gastric cancer patients by machine learning: a multi-cohort study (3 January, 2025)
Ze-Rong Cai, Yong-Qiang Zheng, Yan Hu, Meng-Yao Ma, Yi-Jin Wu, Jia Liu, Lu-Ping Yang, Jia-Bo Zheng, Tian Tian, Pei-Shan Hu, Ze-Xian Liu, Lin Zhang, Rui-Hua Xu, Huai-Qiang Ju

Inflammatory bowel disease

Original research: Reparative immunological consequences of stem cell transplantation as a cellular therapy for refractory Crohn’s disease (17 February, 2025)
Daniela Guisado, Sayali Talware, Xiaoli Wang, Andrew Davis, Elbek Fozilov, Aaron Etra, Jean-Frederic Colombel, Christoph Schaniel, Christopher Tastad, John E Levine, James L M Ferrara, Chuang Ling-Shiang, Ksenija Sabic, Shishir Singh, Bridget K Marcellino, Ronald Hoffman, Judy Cho, Louis Cohen

Coeliac disease

Original research: Purified oat protein can trigger acute symptoms linked to immune activation in coeliac disease patients but not histological deterioration (17 February, 2025) Free
Melinda Y Hardy, Amy K Russell, Lee M Henneken, Greg Tanner, Ferenc Bekes, Ian Brown, Allan Motyer, Sam W Z Olechnowicz, Hugh H Reid, Jamie Rossjohn, Jason A Tye-Din
Original research: Serological screening for coeliac disease in an adult general population: the HUNT study (26 February, 2025)
Ina Lervåg Andersen, Polina Lukina, Ole T Dyrli, Rolf Anton Klaasen, David John Warren, Nils Bolstad, Patricia Mjønes, Elin Rønne, Rasmus Iversen, Ludvig M Sollid, Knut E A Lundin, Eivind Ness-Jensen

Endoscopy

Original research: Carbon footprinting and environmental impact of gastrointestinal endoscopy procedures at a tertiary care institution: a prospective multi-dimensional assessment (4 February, 2025)
Hardik Rughwani, Rakesh Kalapala, Anudeep Katrevula, Nitin Jagtap, Madhav Desai, Sara Teles de Campos, Mohan Ramchandani, Sundeep Lakhtakia, Rupjyoti Talukdar, Santosh Darisetty, Sana Fatima Memon, Guduru Venkat Rao, Marco Bruno, Prateek Sharma, D Nageshwar Reddy

Gut microbiota

Original research:
Dysbiotic oral microbiota-derived kynurenine, induced by chronic restraint stress, promotes head and neck squamous cell carcinoma by enhancing CD8⁺ T cell exhaustion
(4 February, 2025)
Fangzhi Lou, Li Yan, Shihong Luo, Yunmei Dong, Jingyi Xu, Ning Kang, Haiyang Wang, Yiyun Liu, Juncai Pu, Bing Yang, Richard D Cannon, Peng Xie, Ping Ji, Xin Jin

GI cancer

Original research: Trends and cross-country inequality in the incidence of GI cancers among the working-age population from 1990 to 2021: a Global Burden of Disease 2021 analysis (31 December, 2024)
Yiming Song, Xiaoyi Wang, Yufeng Shen, Liping Chen, Liuyi Yang, Ruilan Wang, Junyu Lu, Zhifang Gao, Xiaolu Lin, Yan Song, Qingwei Zhang, Xiaobo Li

Colon

Original research: Early detection of colorectal cancer using aberrant circulating cell-free mitochondrial DNA fragmentomics (18 December, 2024)
Siyuan Wang, Fan Peng, Miao Dang, Huanmin Jiao, Huanqin Zhang, Kaixiang Zhou, Wenjie Guo, Zhiyun Gong, Lin Guo, Renquan Lu, Deliang Li, Bingrong Liu, Xu Guo, Jinliang Xing, Yang Liu

Pancreas

Original research: Risk factors for pancreatic cancer in individuals with intraductal papillary mucinous neoplasms and no high-risk stigmata during up to 5 years of surveillance: a prospective longitudinal cohort study (27 January, 2025)
Tsuyoshi Hamada, Hiroki Oyama, Daniel Nevo, Shuichi Tange, Shinya Takaoka, Yoshikuni Kawaguchi, Kazunaga Ishigaki, Kensaku Noguchi, Tomotaka Saito, Tatsuya Sato, Tatsunori Suzuki, Naminatsu Takahara, Mariko Tanaka, Kiyoshi Hasegawa, Tetsuo Ushiku, Yousuke Nakai, Maxim S Petrov, Mitsuhiro Fujishiro

Hepatology

Original research: Multiomics analysis of immune correlatives in hepatocellular carcinoma patients treated with tremelimumab plus durvalumab (18 February, 2025)
Yuta Myojin, Sepideh Babaei, Rajiv Trehan, Christoph Hoffman, Noemi Kedei, Benjamin Ruf, Mohamed-Reda Benmebarek, Kylynda C Bauer, Patrick Huang, Chi Ma, Cecilia Monge, Changqing Xie, Donna Hrones, Austin G Duffy, Paul Armstrong, Lorenz Kocheise, Fiona Desmond, Jemma Buchalter, Marie Galligan, Colin Cantwell, Ronan Ryan, Jeff McCann, Michele Bourke, Ross Mac Nicholas, Ray McDermott, Joy Awosika, Maggie Cam, Rosanna Krebs, Anuradha Budhu, Mahler Revsine, William D Figg, David E Kleiner, Bernadette Redd, Bradford J Wood, Xin Wei Wang, Firouzeh Korangy, Manfred Claassen, Tim F Greten

Recent advances in basic science

Understanding tissue injury and remodelling in eosinophilic oesophagitis: development towards personalised medicine (10 December, 2024)
Giovanni Santacroce, Carlo Maria Rossi, Marco Vincenzo Lenti, Subrata Ghosh, Marietta Iacucci, Antonio Di Sabatino

Recent advances in clinical practice

Vasomics of the liver (5 March, 2025)
Chengyan Wang, Eric Felli, Jonathan Andrew Fallowfield, Christoph Frank Dietrich, Don Rockey, Jürgen Hennig, Gao-Jun Teng, Jordi Gracia-Sancho, Xiaolong Qi

JournalScan

GI highlights from the literature (7 May, 2025)
Philip J Smith

PostScript

Letter: Sphincterotomy with FCSEMS (SPHINX): a monumental answer or the beginning of new mysteries? (26 November, 2024)
Mohan Ramchandani, Aniruddha Pratap Singh, Rupjyoti Talukdar, D Nageshwar Reddy
Letter: Are histamine-2 receptor antagonists a reasonable comparator: comparing apples and apples? (23 December, 2024)
Lizhi Hu, Yu Peng
Letter: Redefining QUAIDE: paving the way for better AI in preclinical endoscopy (20 December, 2024)
Hui Li, Tiantian Zhang, Qin Guo, Shufen Zhou, Chengshan Guo
Letter: Colonic motility investigation by modern techniques: time to ‘reclaim’ the value of physiology? (31 December, 2024)
Gabrio Bassotti
Letter: SPHINX, a Guardian of Wisdom (31 December, 2024)
Anke Onnekink, Roy L J van Wanrooij, Jeanin E Van Hooft
Letter:
Frequency of de novo PRSS1 pathogenic variants in a French cohort of idiopathic pancreatitis
(31 December, 2024)
Emmanuelle Masson, Anne-Laure Vedie, Frédérique Maire, Tiphaine Godet, Louis Buscail, Vinciane Rebours, Claude Férec, Jian-Min Chen
Letter: Global health inequalities in the burden of gastrointestinal cancers from 1990 to 2021 (11 February, 2025)
Chunlong Liu, Ziqiang He, Jiangtao Yu, Rui Yang
Letter: Revisiting the role of sphincterotomy in sphincter of Oddi disorder: a critical appraisal of the RESPOnD study (29 January, 2025)
Xuefan Zeng
Letter: Response to: correspondence on ‘Revisiting the role of sphincterotomy in sphincter of Oddi disorder: a critical appraisal of the RESPOnD study’ by Zeng (2 April, 2025)
Gregory A Cote

Editor’s quiz: GI snapshot

GI snapshot: arrhythmia, dysphagia and weight loss in a 71-year-old man (10 June, 2024)
Martina De Siena, Loredana Gualtieri, Simone Varca, Maria Valeria Matteo, Valerio Pontecorvi, Vincenzo Bove, Cristiano Spada, Ivo Boškoski

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Current Issue

June 2025 - Volume 74 - 6

Commentaries

Endscopy news

Stomach

Inflammatory bowel disease

Coeliac disease

Endoscopy

Gut microbiota

GI cancer

Colon

Pancreas

Hepatology

Recent advances in basic science

Recent advances in clinical practice

JournalScan

PostScript

Editor’s quiz: GI snapshot

Issue Information

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Current Issue

June 2025 - Volume 74 - 6

Commentaries

Endscopy news

Stomach

Inflammatory bowel disease

Coeliac disease

Endoscopy

Gut microbiota

GI cancer

Colon

Pancreas

Hepatology

Recent advances in basic science

Recent advances in clinical practice

JournalScan

PostScript

Editor’s quiz: GI snapshot

Issue Information