Footnotes

• DRQ and JJM contributed equally.

• Contributors DRQ and JJM contributed equally.

• Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

• Competing interests DRQ has received a research award sponsored by Sanofi; has received honoraria for lectures, presentations, and educational events by Eli Lilly & Co. and Novo Nordisk; has received support for attending meetings and/or travel from Eli Lilly & Co. and Cook Medical. JJM has received lecture honoraria and consulting fees from AstraZeneca, Berlin-Chemie, Boehringer Ingelheim, Eli Lilly, Merck Sharp & Dohme (MSD), Novo Nordisk, Novartis and Sanofi; has received reimbursement of congress participation fees and travel expenses from MSD, Novo Nordisk, and Sanofi; and has initiated projects supported by Boehringer-Ingelheim, MSD, Novo Nordisk and Sanofi.

• Provenance and peer review Not commissioned; externally peer reviewed.