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Recently, Jarosova et al 1 carried out a multicentre randomised trial to assess the impact of endoluminal radiofrequency ablation (RFA) plus stenting with stenting alone in patients with malignant biliary obstruction. The authors demonstrated that there was no benefit of endoluminal biliary RFA in patients with cholangiocarcinoma (CCA) and pancreatic cancer on survival or stent patency.
Their results were in agreement with the only Western randomised controlled study conducted by Albers et al.2 We notice that hilar CCA accounted for a large proportion (85.9%, 73/85) in CCA arm of the current study while distal biliary strictures accounted for 62.8% (54/86) in the latter study. We believe that the type of tumour and the location of the stenosis may have some impact on overall …
Footnotes
Contributors JF and Z-SL conceived and designed the study. J-SL wrote the draft. All authors: final approval of the letter.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; internally peer reviewed.