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Acute paediatrics
West Nile virus meningoencephalitis complicated by motor aphasia in Hodgkin's lymphoma
  1. R Spiegel1,
  2. D Miron2,
  3. H Gavriel3,
  4. Y Horovitz1
  1. 1Pediatric Department A', Ha'Emek Medical Center, Afula, Rappaport School of Medicine, Technion, Haifa, Israel
  2. 2Pediatric Infectious Disease Division, Ha'Emek Medical Center
  3. 3Pediatric Hematology-Oncology Department, Ha'Emek Medical Center
  1. Correspondence to:
    Dr R Spiegel, Department of Pediatrics A, Ha'Emek Medical Center, Afula 18101, Israel;
    spiegelr{at}internet-zahav.net

Abstract

A 4 year old boy with Hodgkin's lymphoma was admitted to the paediatric ward with meningoencephalitis dominated by generalised seizures and motor aphasia. Serum IgM specific antibodies to West Nile virus were positive. In view of ongoing neurological deterioration and immunocompromised state he was treated with oral ribavirin for 14 days. A gradual improvement was noted within two weeks of therapy initiation, and with intensive supportive care he recovered completely after four months.

  • Hodgkin's lymphoma
  • West Nile fever
  • meningoencephalitis
  • ribavirin
  • ANC, absolute neutrophil count
  • CNS, central nervous system
  • CRP, C reactive protein
  • CSF, cerebrospinal fluid
  • EBV, Epstein
  • Barr virus
  • PCR, polymerase chain reaction
  • WBC, white blood cell
  • WNF, West Nile fever
  • WNV, West Nile virus

https://doi.org/10.1136/adc.86.6.441

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