PEPtalk2: results of a pilot randomised controlled trial to compare VZIG and aciclovir as postexposure prophylaxis (PEP) against chickenpox in children with cancer

Jessica Bate; Stephen Baker; Judith Breuer; Julia C Chisholm; Juliet Gray; Sophie Hambleton; Aimee Houlton; Mark Jit; Stephen Lowis; Guy Makin; Catherine O’Sullivan; Soonie R Patel; Robert Phillips; Neil Ransinghe; Mary Elizabeth Ramsay; Roderick Skinner; Keith Wheatley; Paul T Heath

doi:10.1136/archdischild-2017-314212

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Original article

PEPtalk2: results of a pilot randomised controlled trial to compare VZIG and aciclovir as postexposure prophylaxis (PEP) against chickenpox in children with cancer

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Jessica Bate Department of Paediatric Oncology, University Hospital Southampton NHS Foundation Trust, Southampton, UK PubMed articles Google scholar articles
Stephen Baker Cancer Research UK Clinical Trials Unit (CRCTU), School of Cancer Sciences, University of Birmingham, Birmingham, UK PubMed articles Google scholar articles
Judith Breuer Division of Infection and Immunity, University College London, London, UK PubMed articles Google scholar articles
Julia C Chisholm Children and Young People’s Unit, Royal Marsden NHS Foundation Trust, Sutton, UK PubMed articles Google scholar articles
Juliet Gray Department of Paediatric Oncology, University Hospital Southampton NHS Foundation Trust, Southampton, UK Cancer Sciences Academic Unit, University of Southampton, Southampton, UK PubMed articles Google scholar articles
Sophie Hambleton Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK Great North Children’s Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK PubMed articles Google scholar articles
Aimee Houlton Cancer Research UK Clinical Trials Unit (CRCTU), School of Cancer Sciences, University of Birmingham, Birmingham, UK PubMed articles Google scholar articles
Mark Jit Modelling and Economics Unit, Public Health England, London, UK Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK PubMed articles Google scholar articles
Stephen Lowis School of Clinical Sciences, University of Bristol, London, UK PubMed articles Google scholar articles
Guy Makin Division of Cancer Sciences, University of Manchester, Manchester, UK PubMed articles Google scholar articles
Catherine O’Sullivan Paediatric Infectious Diseases Research Group and Vaccine Institute, Institute of Infection and Immunity, St. Georges, University of London, London, UK PubMed articles Google scholar articles
Soonie R Patel Department of Paediatrics, Croydon Health Services NHS Trust, London, UK PubMed articles Google scholar articles
Robert Phillips Leeds Children’s Hospital, Leeds, UK PubMed articles Google scholar articles
Neil Ransinghe Parent representative, Paediatric Oncology Reference Team, UK PubMed articles Google scholar articles
Mary Elizabeth Ramsay Immunisation Department, Public Health England, UK PubMed articles Google scholar articles
Roderick Skinner Great North Children’s Hospital, Department of Paediatric and Adolescent Haematology/Oncology, Newcastle upon Tyne, UK PubMed articles Google scholar articles
Keith Wheatley Cancer Research UK Clinical Trials Unit (CRCTU), School of Cancer Sciences, University of Birmingham, Birmingham, UK PubMed articles Google scholar articles
Paul T Heath Paediatric Infectious Diseases Research Group and Vaccine Institute, Institute of Infection and Immunity, St. Georges, University of London, London, UK PubMed articles Google scholar articles

Correspondence to Dr Jessica Bate, Department of Paediatric Oncology, University Hospital Southampton NHS Foundation Trust, Southampton, SO16 9YD, UK; jessica.bate1{at}nhs.net

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Citation

Bate J, Baker S, Breuer J, et al

PEPtalk2: results of a pilot randomised controlled trial to compare VZIG and aciclovir as postexposure prophylaxis (PEP) against chickenpox in children with cancer

Archives of Disease in Childhood 2019;104:25-29.

Publication history

Received October 2, 2017
Revised February 16, 2018
Accepted April 17, 2018
First published May 5, 2018.

Online issue publication

August 06, 2019

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