Cochrane Clinical Answers

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Cochrane Clinical Answers (CCAs) provide a readable, digestible, clinically focused entry point to rigorous research from Cochrane systematic reviews. They are designed to be actionable and to inform decision making at the point of care and have been added to relevant sections of the main Best Practice text.

  • How does tofacitinib compare with placebo for maintaining remission in people with ulcerative colitis?
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  • Is there randomized controlled trial evidence to support the use of etrolizumab for induction of remission in people with ulcerative colitis?
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  • What are the effects of antibiotics for the induction and maintenance of remission in people with ulcerative colitis?
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  • For maintenance of remission in people with ulcerative colitis, how do probiotics compare with mesalazine (5‐ASA)?
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  • Can adding probiotics to standard concomitant drug treatment improve outcomes over standard treatment alone in adults and children with ulcerative colitis?
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  • What are the effects of fecal microbiota transplantation (FMT) for people with ulcerative colitis?
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  • How does surveillance compare with no surveillance for detecting colon cancer in people with ulcerative colitis or inflammatory bowel disease?
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